Duac Gel (3% or 5%)

Instead of masking the issue, Duac directly combats the source to prevent the growth of bacteria under the skin cells that cause spots and pimples. It comes as an easy-to-use topical gel that you can buy Duac online by completing a consultation. The entire process is completed online without the need to visit your doctor or the pharmacy. We offer free next working day delivery.

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What is Duac Gel (3% or 5%)?

Duac Gel (3% or 5%) is used in the treatment of mild to moderate acne, an inflammatory skin condition that causes spots.

Duac Gel contains two complementary ingredients: clindamycin phosphate, an antibiotic and benzoyl peroxide, a keratolytic. Together, these ingredients fight the cause of acne and help prevent inflammation and spots.

Duac Gel (3% or 5%) is only recommended for use in adults and adolescents aged 12 years and over. It is not recommended for use in children under the age of 12 as its safety has not been established for this group.

If you are pregnant, you should always seek medical advice from your doctor before using this medicine. Although it is not thought to be harmful for use during pregnancy, it should be used with caution.

If you are breastfeeding, you should only use Duac Gel if considered essential by your doctor. Clindamycin phosphate passes into breast milk when taken by mouth, and the safety of Duac Gel has not been established. Do not apply the gel to areas where it could come into contact with a baby during a feed or touch baby's skin.

Do not use Duac Gel if you are allergic to any of the ingredients.

How does Duac Gel (3% or 5%) work?

Duac Gel (3% or 5%) contains two active ingredients which work together to fight acne.

Propionibacterium acnes, bacteria associated with acne, feed on sebum and produce waste products that cause inflammation of the sebaceous glands, causing spots.

Duac Gel contains the antibiotic clindamycin phosphate, which is effective against Propionibacterium acnes. This ingredient controls the number of bacteria, reducing inflammation while letting skin heal.

This gel also contains benzoyl peroxide, a common ingredient in many acne medicines. Benzoyl peroxide is a keratolytic. This means it breaks down keratin in the skin's structure, resulting in a shedding of the top layer of skin cells.

This helps to unblock the sebaceous glands while breaking down whiteheads and blackheads (comedones). It also helps to prevent the formation of new comedones and has an additional antibacterial action.

It is important to continue using Duac Gel (3% or 5%) for as long as your doctor advises. This is because it can take 2-6 weeks before the full effect of both ingredients is noticeable on your skin.

If you do not see an improvement in your acne within 6 weeks of using this medicine, seek advice from your doctor.

How to use Duac Gel (3% or 5%)

  • Wash your skin (use a mild cleanser) and pat it dry before application
  • Apply a thin layer of Duac Gel (3% or 5%) to the affected area(s) of skin once a day
  • For best results this gel should be applied at night and rubbed in gently
  • Wash your hands after applying the gel
  • Do not apply the gel to sunburnt, irritated or broken skin
  • Do not use too much gel, as this can increase the risk of skin irritation

What dosages are available for Duac Gel (3% or 5%)?

There are two dosages available for Duac Gel.

For the 3% dosage, 1g of gel contains 10mg (1% w/w) of clindamycin as clindamycin phosphate and 30mg (3% w/w) of anhydrous benzoyl peroxide as hydrous benzoyl peroxide.

For the 5% dosage, 1g of gel contains 10mg (1% w/w) of clindamycin as clindamycin phosphate and 50mg (5% w/w) of anhydrous benzoyl peroxide as hydrous benzoyl peroxide.

This medicine is available only by prescription from your doctor.

What are the side effects of Duac Gel (3% or 5%)?

Although most people can use Duac Gel without experiencing any side effects, medicines affect people differently and you may experience side effects.

Side effects which have been commonly reported include: itching, dryness, redness and irritation at the site of application; dermatitis; and, headache. Other less common side effects include: a rash at the point of application; pins and needles; an allergic reaction; or, a worsening of acne.

If you are concerned about these or any other side effects, speak to your doctor.

What are the precautions/interactions of Duac Gel (3% or 5%)?

You should always tell your doctor about any other medicines you are taking, or have recently taken, as there is a chance they could interact with Duac Gel.

You should not use Duac Gel if you are using products containing erythromycin (an antibiotic). There are a number of medication interactions all detailed in the patient leaflet, which should be read thoroughly before use.

If you are taking Roaccutane or isotretinoin orally as an acne treatment, you should not use Duac Gel as this can increase the risk of peeling, irritation and dryness of your skin.

Benzoyl peroxide can reduce the effectiveness of topical products containing tazarotene, isotretinoin and tretinoin. If you are using any of these products you should not use Duac Gel at the same time, as irritation may also occur. If you need to use both products, apply them at different times (for example, one in the morning and the other at night).

Using other topical acne medicines at the same time as Duac Gel (such as soaps, cleansers and medicated cosmetics) can increase the risk of skin irritation and peeling.

You should not use this medicine if you have very sensitive skin or skin prone to eczema.

Duac Gel should not be used for more than 12 weeks at a time.

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