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Home / Erectile Dysfunction / Compare Prescription Impotence Treatments

Compare Prescription Impotence Treatments

Most Popular - Viagra
  • Effective for up to 4 hours
  • Works in 30-60 minutes
  • 1st treatment on the market
Viagra 50mg
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With multiple erection pills available in the UK, it can be a struggle knowing which is going to be the best for your lifestyle. Whilst the level of choice is great, each male erection pill has its advantages and disadvantages. Here we analyse and compare the top erection pills on the UK market so you can make a simple choice.

Which erection pills are we comparing?

On this page, we will research prescription medications such as Viagra. This means all the medications have been clinically tested and approved in the UK.

There are a number of these available in the UK; whilst the objective is the same, how they're ingested and the potency level have subtle differences. This means that even if you suffer from cardiovascular diseases such as high blood pressure, it is highly likely that there is still an erectile dysfunction medication suitable for you.

We will be comparing:

  • Viagra
  • Sildenafil
  • Cialis
  • Cialis Once Daily
  • Tadalafil
  • Levitra
  • Levitra Orodispersible
  • Spedra

You cannot buy these over-the-counter in the pharmacy or high street stores; they require a prescription slip from a doctor to ensure your health isn't at risk or you won't experience severe side effects.

This can be obtained during a face-to-face doctor's appointment, or you can order online. At HealthExpress we offer a whole range of prescription medications for erectile dysfunction. If you're unsure which is most suitable for you, you can check our table below, or just begin a free consultation to be recommended the ideal erection pill for you.

If you wish to discover more about herbal and natural supplements for erectile dysfunction, you can do so on our dedicated herbal treatment page. This includes products such as horny goat weed, ginseng, and fenugreek.

Comparing prescription erection pills

Viagra (sildenafil), Levitra (vardenafil) and Cialis (tadalafil) are all highly effective FDA approved medications that treat erectile dysfunction. While each work in similar ways, there are subtle differences in how quickly they act, how long they last, their effectiveness, their side effects and their interactions with other substances. It is important to understand these differences so you can find the treatment that most suits you and your lifestyle.

Use the orange scroll along the top to see a simple comparison between prescription treamtents available in the UK:

Medication Viagra Sildenafil Cialis Cialis Once Daily Tadalafil Levitra Levitra Orodisperible Spedra
Medication Packaging Viagra sildenafil Cialis Cialis Once a Day Tadalafil Levitra Levitra Orodispersible spedra
Manufacturer Pfizer Sandoz Lilly Lilly Actavis Bayer Bayer Menarini
Active Ingredient Sildenafil Sildenafil Tadalafil Tadalafil Tadalafil Vardenafil Vardenafil Avanafil
How long it lasts 4 hours 4 hours 36 hours Continually if taken once a day 36 hours 5 hours 5 hours 6 hours
Effective within… 30 minutes 30 minutes 30 minutes Continually if taken once a day 30 minutes 15 minutes 15 minutes 15 minutes
Common Side Effects Headache, stuffy nose, facial flushing Burning eyes, flushing, sneezing Headache, backache, muscle aches Headaches, facial flushing, stuffy nose, muscle aches Headache, stuffy nose, facial flushing headache, stuffy nose Headaches, facial flushing, stuffy nose, muscle aches Headache, facial flushing, stuffy nose
Advantages Reliable, recognised, available in multiple dosages, fairly tolerable Reliable, cheaper version to Viagra, available in multiple dosages, fairly tolerable Long-lasting, lower dosages, highly tolerable Only daily treatment available, low dosages, offer spontenity, highly tolerable Long-lasting, cheaper version to Cialis, highly tolerable Fast-acting, low dosages, highly tolerable The only dissovable treatment, fast-acting, low dosages, highly tolerable Fastest of all ED meds, available in high dosages, last in the system for up to 6 hours
Take only when needed right-tick right-tick right-tick cross-tick right-tick right-tick right-tick right-tick
Taken daily cross-tick cross-tick cross-tick right-tick cross-tick cross-tick cross-tick cross-tick
Nickname Blue Pill NA Weekend Pill Daily Pill NA NA NA NA
What will the pill looks like? Viagra Tablet sildenafil Tablet Cialis Tablet Cialis Daily Tablet Tadalafil Tablet Levitra Tablet Levitra Orodispersible Tablet spedra Tablet
Dosages 25mg, 50mg and 100mg 25mg, 50mg and 100mg 10mg and 20mg 2.5mg and 5mg 5mg, 10mg and 20mg 5mg, 10mg and 20mg 10mg 50mg, 100mg and 200mg
Prescription only right-tick right-tick right-tick right-tick right-tick right-tick right-tick right-tick
Suitable for women cross-tick cross-tick cross-tick cross-tick cross-tick cross-tick cross-tick cross-tick
Taken without food right-tick right-tick right-tick right-tick right-tick right-tick right-tick right-tick
Taken with food Yes, but may reduce effectiveness Yes, but may reduce effectiveness Yes, but may reduce effectiveness Yes, but may reduce effectiveness Yes, but may reduce effectiveness Yes, but may reduce effectiveness Yes, but may reduce effectiveness Yes, but may reduce effectiveness

How do they work?

Whilst there is differences in how long they last and when they become effective, erectile dysfunction treatments all work in the same way; they are classed as phosphodiesterase (PDE) inhibitors. They work by restricting the enzyme PDE-5, allowing more blood to flow to your penis. The key benefit of these medications is that this effect will only occur when you're sexually aroused.

Viagra was the first medication to launch and is probably the most famous of the erection pills. It was first approved as a treatment for erectile dysfunction in 1998. Levitra followed with its approval for use in August 2003 and later that year, in November, Cialis was approved. Many erection pills are also available in their "generic version".

Do the erection pill test

This impotency test takes 7 questions to establish which erectile dysfunction treatment is best for you. A consultation may require additional information, but this can give you a realistic starting point.

Based on a selection of questions, we can recommend the best erection pill for your lifestyle:

Which erection pill is most effective?

Structurally Viagra's active ingredient, Sildenafil, and Levitra's active ingredient, Vardenafil, are very similar. They both stay in your system and are effective for about 4-6 hours. Cialis's active ingredient Tadalafil is markedly different, which is seen by its long lasting nature. It can be effective for up to 36 hours.

In terms of their effectiveness rates, they are all highly successful treatments for erectile dysfunction. Ranked from high to low:

  • Viagra has an 84% success rate
  • Sildenafil has an 84% success rate
  • Levitra and Levitra Orodispersible has an 81% success rate
  • Cialis and Cialis Once Daily has an 80% success rate
  • Tadalafil has a 80% success rate
  • Spedra has a 58% success rate

*Be aware that these stats are subject to the dosage amount, higher dosages usually result in a higher success rate.

Which erection pill lasts the longest?

Whilst this can be dependant on the individual, Cialis is generally considered the best option if you want a medication that stays in the system for the longest amount of time.

Cialis in 10mg and 20mg can last up to 36 hours and is therefore referred to as the weekend pill. This doesn't mean you have an erection continually for 36 hours! You will be able to gain an erection when sexually aroused, like all impotence medications.

Cialis Daily is taken daily and remains in your system 24/7. It is available in low dosages and offers further spontaneity.

Saying this, other erection pills can last in the system for up to 8-10 hours, which may also be an ideal amount of time.

I would like continual erectile dysfunction medication

If you are, or want to be, very sexually active then an option like Cialis Daily means you'll be able to have sex without the need to ingest a pill around an hour beforehand. This offers further spontaneity and is particularly handy for men who have sex multiple times a week.

Cialis Daily is taken once a day, every day, and remains in your system continually until you decide to stop taking it. It is therefore available in a lower dosage of 2.5mg or 5mg.

I'd like my treatment to work quickly

Erection pills tend to work within an hour of digestion. Once you begin using a particular treatment, you'll become accustomed to how long the pills last, and how quickly they take to work.

Whilst 30-60 minutes is a fairly quick amount of time, the fastest erection pill can work in as little as 15 minutes; Spedra. Another option is Levitra that can work in around 15-30 minutes depending on the individual.

There are certain components that can slow down and lessen the effectiveness of erection pills. This includes drinking alcohol or having a large meal beforehand. Limiting these factors offer optimum effectiveness.

I'm prone to side effects

All erection pills mentioned on this page require a consultation by a certified doctor before you can order. This means the doctor has assessed the likelihood of side effects and if approved, this means the pros outweigh the cons.

Whilst it is dependant on the individual in question, Cialis and Levitra are generally considered as the most tolerant as they are available in a range of smaller dosages.

Common side effects Viagra Sildenafil Cialis Cialis Once Daily Levitra Levitra Orodispersible Spedra
Headache dot mark dot mark dot mark dot mark dot mark dot mark dot mark
Indigestion dot mark dot mark dot mark dot mark dot mark dot mark dot mark
Dizziness dot mark dot mark dot mark dot mark dot mark dot mark
Facial flushing dot mark dot mark dot mark dot mark dot mark dot mark dot mark
Muscle aches dot mark dot mark
Nasal congestion dot mark dot mark dot mark dot mark dot mark dot mark dot mark
Back pain dot mark dot mark dot mark
Nausea dot mark
Change in/reduced vision dot mark dot mark
Don't take it if you have: Viagra Sildenafil Cialis Cialis Once Daily Levitra Levitra Orodispersible Spedra
Had a recent stroke or heart attack dot mark dot mark dot mark dot mark dot mark dot mark dot mark
Heart disease dot mark dot mark dot mark dot mark dot mark
Low blood pressure dot mark dot mark dot mark dot mark dot mark dot mark dot mark
Uncontrolled high blood pressure dot mark dot mark
Ever had a loss of vision dot mark dot mark dot mark dot mark dot mark
Inherited eye problems dot mark dot mark dot mark dot mark dot mark dot mark dot mark
Liver or kidney problems dot mark dot mark dot mark dot mark dot mark
If you are on dialysis dot mark dot mark
If you are taking nitrates dot mark dot mark dot mark dot mark dot mark dot mark dot mark
If you are taking ritonavir or indinavir for HIV dot mark dot mark

With ED medication, if you have had no prior health issues that can warrant side effects, your doctor will usually offer you the middle dosage and adjust from here if necessary.

The erection pills that offer the strongest erection

No erection pills advertise themselves as offering "strong erections"; this might be a welcomed side effect, or you may notice no changes regarding this aspect. This is going to be trial and error and will be dependant on the individual, however, there are some sources:

From customer research in the past, Sildenafil and its branded version Viagra have been the erection pills that have caused the strongest erection, however, this could be down to the fact that there is more data available for these medications.

Erection pills containing a higher dosage may offer stronger erections, but also a higher risk of side effects.

As Cialis is available in lower dosages and these pills tend to work over a longer period, these are reported as giving weaker erections than other erection pills, but still sufficient nonetheless.

What erection pill is most cost-effective?

Both Cialis and Viagra are available as a generic product known as Tadalafil and Sildenafil respectively. "Generic medication" means that it contains the same active ingredient as the branded versions but will often be cheaper. You may also find bulk-buying to work out cheaper in the long-run, especially if you require erection pills consistently.

Viagra vs Cialis

Viagra is the most well-known erection pill, but Cialis is also a popular choice. They both have their pros and cons. If you're looking for a long-lasting pill, Cialis would be better whilst stronger erections have been reported with Viagra.

Medication Viagra Cialis
Medication packaging Viagra Cialis
Active ingredient Sildenafil Tadalafil
Dosages 25mg, 50mg, 100mg 10mg, 20mg
Effective within… 60 minutes 30 minutes
Lasts for… Up to 5 hours Up to 36 hours
When it is most potent Around 90 minutes Around 120 minutes
Strong erection? Very high High
Advantages Recognisable, first approved, high success rate Longest lasting ED med, low dosage, minimum side effect risk

The main difference between Viagra and Cialis is the amount of time the drugs stay in the system. Cialis can last up to 36 hours, whilst Cialis Daily remains in your system 24/7 if you take one pill every day. If you have been approved both Viagra and Cialis by a certified doctor, there is no reason why you can try both and see what works best for you.

When trying multiple erection pills, you must leave at least 24 hours between each type of pill.

Viagra vs Levitra

Both Viagra and Levitra have a similar effect and last for the same duration, depending on the dosage. If you're looking for an erection pill that works quickly, as you can see, Levitra works in around 30 minutes compared to 60 minutes for Viagra.

Medication Viagra Levitra
Medication packaging Viagra Levitra
Active ingredient Sildenafil Vardenafil
Dosages 25mg, 50mg, 100mg 5mg, 10mg, 20mg
Effective within… 60 minutes 30 minutes
Lasts for… Up to 5 hours Up to 5 hours
When it is most potent Around 90 minutes Around 60 minutes
Strong erection? Very High High - Very High
Advantages Recognisable, first approved, high success rate Works quickly, low dosages, minimum risk of side effects

Like Viagra vs Cialis, one of the significant differences comes with how you take the medication. Viagra and Levitra come in the form of a tablet easily swallowed with water. However, Levitra is also available in Levitra Orodispersible; a small discreet tablet that dissolves on the tongue with a minty aftertaste.

Viagra vs Sildenafil

Viagra and Sildenafil contain the same active ingredient (sildenafil) and are used in exactly the same way. The preference is down to whether you prefer branded medication or generic, is down to you but the generic versions of medication are often more cost-effective.

Viagra vs Spedra

The main difference between Viagra and Spedra is the speed in which each works. Spedra is available in higher dosages (therefore increasing your risk of experiencing side effects) but this does mean it can works in as little as 15 minutes compared to Viagra's 30-60 minutes. This is, again, dependant on the individual. Also, if this does mean you experience side effects, you may find the longer wait more beneficial in the long-run.

Medication Viagra Spedra
Medication packaging Viagra spedra
Active ingredient Sildenafil Avanafil
Dosages 25mg, 50mg, 100mg 50mg, 100mg, 200mg
Effective within… 60 minutes 15 minutes
Lasts for… Up to 5 hours Up to 6 hours
When it is most potent Around 90 minutes Around 45 minutes
Strong erection? Very High NA
Advantages Recognisable, first approved, high success rate Fastest acting ED treatment, high dosages

Want to order erection pills?

If our tools have helped you make your decision, complete a free consultation for the product of your choice. Our partner doctor will confirm that the medication is right for you.

If you're still unsure, you can still complete a condition consultation and our doctor will recommend the best treatment for you based on your medical history and current condition status.

All consultations are 100% confidential, as well as the free next-day delivery, meaning you can get your preferred erection pills delivered straight to your workplace or shared accommodation.

Usage and dosage options

All of these medications are oral tablets, and in all cases, dosage should not exceed one tablet in a 24-hour period.

Both Viagra and Levitra should be taken 30-60 minutes before intercourse. The usual starting dosage for Viagra is 50mg, but this can be adjusted up to 100mg or down to 25mg as required. Levitra's active ingredient vardenafil is more potent than sildenafil, and as a result, a lower dosage is required. The recommended dosages for Levitra is 10mg, which can be adjusted to 20mg.

Cialis's active ingredient tadalafil works quite differently and there are two types of prescriptions available. Cialis is available in 10mg, which can be increased to 20mg dosages. It can be taken from 30 minutes to 12 hours before planned intercourse and lasts for up to 36 hours. The second form of Cialis, Cialis Daily is also available. This involves taking a 2.5mg (or 5mg) tablet daily. It may take a few days for enough of the drug to build up in your system to be effective, but by taking it daily you can ensure constant results which allows for much greater spontaneity.

Sources: