Prices include next-day delivery and prescription
|56 tablets||£94.99||Save £3.00|
|84 tablets||£139.99||Save £7.00|
More information about Linagliptin
Linagliptin, also known under the brand names ‘Tradjenta’ and ‘Trajenta’, is a clinically proven treatment for high blood sugar levels in those with type 2 diabetes. It is often prescribed to those who have not responded well to other anti-diabetic drugs such as biguanides (like Metformin); sulphonylureas (like Glimepiride); glitazones (Thiazolidinedione and Pioglitazone) GLP-1 and SLGT-2 inhibitors (like Empagliflozin).
It is recommended that this medication is used alongside a healthy diet and exercise regime. It is also not suitable for those with type 1 diabetes, so if you’re seeking treatment for type 1 diabetes, please contact your GP or diabetes healthcare professional.
You can buy Linagliptin from HealthExpress for the treatment of type 2 diabetes. It is only available on prescription, so you will need to fill out a short consultation form, which will be reviewed for suitability by one of our doctors.
Linagliptin, alongside Sitagliptin and Saxagliptin, belongs to a group of oral anti-diabetic drugs known as DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). These drugs work by blocking the DPP-4 enzyme which destroys gastrointestinal hormones called incretins.
Incretins help stimulate the secretion of the hormone insulin after eating and reduce the production of the hormone glucagon by the liver during digestion when it is not needed. So therefore, Linagliptin protects incretins through the inhibition of DPP-4 so that they can regulate blood sugar levels. This will keep your blood sugars low and prevent hyperglycemia, which is where your blood glucose levels are critically low.
The active ingredient, linagliptin, can also be found in combination therapies with other ingredients such as Metformin (Jentadueto). Here at HealthExpress, we only offer Linagliptin on its own (monotherapy).
Linagliptin comes in the form of 5mg tablets. Always follow your doctor’s advice on how to take it, but generally, you should take one tablet once a day. You do not need to take them with food, but you should try and take them at the same time each day.
If you forget to take a dose, take it as soon as you remember. However, if it's nearly time for your next dose, then do not take the missed dose. You should not take two doses of Linagliptin in one day. If you take more Linagliptin than you should, contact your doctor immediately.
Like all prescription medications, Linagliptin can cause some side effects. For an extensive list of side effects, please refer to the patient information leaflet.
One of the most common side effects of Linagliptin, especially when taken with other diabetes medications, is hypoglycemia or ‘hypo’. It can occur in 1 in 10 people who take Linagliptin with other antidiabetics, so if you experience the following symptoms you should seek medical attention:
More uncommon (1 in 100) side effects may include: an allergic reaction such as swelling, hives or skin problems; a condition where your nose is inflamed called nasopharyngitis; cough and constipation. In very rare cases (1 in 1000), you can experience more serious side effects. Some who take Linagliptin may experience inflammation of the pancreas (pancreatitis). If you experience persistent pain in the abdomen that often travels to your back as well as nausea and vomiting, then you should seek medical attention. Pancreatitis is still a very rare side effect and incidence is low.
Litagliptin does not cause weight loss or weight gain.
Only adults with type 2 diabetes mellitus can be prescribed this medication. Therefore, it is not suitable for the treatment of type 1 diabetes or those with diabetic ketoacidosis (high levels of ketones in the blood or urine). You should also not take this medicine if you’re pregnant or breastfeeding as this could potentially harm the baby. It is also not recommended for children under the age of 18.
There are some other groups of people who should take caution using this medication, as they are at a higher risk of side effects. This includes those who have or have had:
There may also be drug interactions if Linagliptin is taken with any of the following medicines:
If you think you fall under any of these groups or take any of these medications, speak to your GP or a healthcare professional before taking Linagliptin.
Some DPP-4 inhibitors have been linked to heart failure, especially in those who have coronary heart disease (atherosclerotic cardiovascular disease) and/or kidney dysfunction (renal impairment). However, clinical trials have found that there was no increased risk of heart failure, other cardiovascular diseases and kidney disease in those who took Linagliptin.
One study randomly assigned groups of patients with type 2 diabetes who had coronary heart disease and/or kidney disease to either receive Linagliptin treatment or a placebo (inactive) treatment. They found that Linagliptin did not affect the risk of heart failure and heart failure-related complications.
Other antidiabetic medications have been linked to rare cases of liver dysfunction. Certain clinical case studies have found that some antidiabetic medications cause hepatotoxicity (toxic liver disease), a term used to describe liver damage caused by medicines, herbal supplements, chemicals, solvents and alcohol.
Whilst those who are predisposed to liver damage or have liver problems should always be cautious when taking new medications, clinical studies of DPP-4 inhibitors have not found a similar link. In fact, several studies have found that DPP-4 inhibitors improve liver dysfunction, especially particular conditions such as NAFLD (non-alcohol related fatty liver disease). Pharmacokinetic studies have also found that those who have hepatic impairment do not need their dose of Litagliptin altered.
You can buy Linagliptin for type 2 diabetes here at HealthExpress if you have a formal diagnosis for the condition. If you think you have type 2 diabetes and haven’t had a formal diagnosis, you should speak to your GP as diabetes can present similar symptoms to other conditions.
You will need to fill in a short consultation form with your medical history, then one of our registered doctors will review it. This is to make sure Linagliptin is suitable for you. Once our doctors have assessed it, your prescription will be dispensed and dispatched by our pharmacy with free next-day delivery.
|Manufacturer||Boehringer Ingelheim Ltd.|
|Description||An anti-diabetic treatment for adults with diabetes|
|Exemption||Subject to medical prescription|
|Application||One tablet taken daily|
|Posology||Consult patient leaflet|
|Drug class||Dipeptidyl peptidase-4 (DPP- 4) Inhibitors|
|Alcohol consumption||In moderation|
|When breastfeeding||Speak to your doctor|
|When pregnant||Speak to your doctor|
Note: Decisions about treatment are for both the prescriber and the person to jointly consider during the consultation. However, the final decision will always be the prescriber’s.