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Home Diabetes Onglyza


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Dr. Sarah Donald
Dr. Sarah Donald Clinical Lead

"Our medical team is always on hand to ensure that you get the safest and most effective treatment. Your medication will be dispatched the same day from our pharmacy."

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Onglyza FAQs

What is Onglyza?

Onglyza (saxagliptin) is a once-daily, oral type-2 diabetes treatment, used to treat diabetes by controlling blood sugar levels. It is prescribed particularly for individuals with type 2 diabetes, and is often used in combination with other diabetes treatments, but is never used to treat type 1 diabetes. It essentially works by controlling and regulating insulin levels your body produces after eating. For the best results, it should be taken alongside an effective diet and exercise regime, and it has been fully regulated for use in the UK.

How does Onglyza work?

Onglyza is known as a dipeptidyl peptidase-4 (DPP-4) inhibitor, and contains the active ingredient, saxagliptin. This group of anti-diabetic medications operate in the same way, by stimulating the digestive hormones that are responsible for increasing the levels of insulin released after eating. These hormones are called 'incretin' hormones, and force the pancreas to produce more insulin when glucose levels in your blood are high. Insulin is crucial in the effective control of blood sugar levels in people with from diabetes.

What are the benefits of Onglyza?

Onglyza (saxagliptin) comes with a number of benefits that you can experience, when using the treatment correctly.

  • Onglyza has been proven by clinical studies to control high blood sugar (hyperglycaemia) in combination with diet and exercise
  • As well as its effectiveness, Onglyza is available in tablet form, which means it is convenient to take
  • This medication is recommended, if diet and exercise and other oral diabetic medications haven't succeeded in controlling your glucose levels
  • Onglyza (saxagliptin) can be used in combination with insulin and other diabetes treatments
  • Unlike some other diabetes medications, Onglyza doesn't encourage weight gain
  • Onglyza has been proven effective for many with type 2 diabetes in the UK

Usage/dosages of Onglyza (saxagliptin)

Onglyza comes in tablet form, and is currently available in a 2.5mg and 5mg dosage. If you have kidney problems, the doctor may recommend that you use the 2.5 mg dose, rather than the 5 mg dose. Your doctor will suggest the ideal dose before issuing the treatment. This is whether it is in person or online.

You should take one tablet daily and, unlike other medications for type 2 diabetes, you can take your tablet with or without food. Remember to take Onglyza exactly as advised. If you want to change your dose, then always consult with a doctor or nurse. Onglyza can be combined with other medications such as metformin, gliclazide and thiazolidinedione.

Who can take Onglyza?

Onglyza is an effective treatment for people with type 2 diabetes whose blood sugar is not sufficiently regulated by other anti-diabetic medications. Onglyza is not suitable for everyone, so always tell your doctor if you have kidney problems, are pregnant or are known to have problems with your heart. This medication is not suitable for people who are allergic to any of the ingredients, so you must always check the label and the patient information leaflet before taking this medication. The patient leaflet is available at the bottom of this page as well.

What are the side effects of Onglyza?

All prescription medications approved in the UK come with the risk of possible side effects, however these are small and affect people in different ways. For example, they could be completely manageable or require a change of treatment.

The more common potential side effects associated with Onglyza (saxagliptin) are indigestion, muscle pains, fatigue and dizziness, and even these only happen to a small percentage of users. The uncommon side effects include inflammation of the pancreas, allergic reactions and dermatitis. Often, these adverse reactions will disappear once your body has become accustomed to the medication and are generally highly unlikely to occur.

What are the precautions for Onglyza?

Before taking Onglyza (saxagliptin) , it is important to consider any precautions and interactions associated with the treatment. These include:

  • Inactive ingredients in Onglyza can cause allergic reactions - It is important to consider your own allergies before taking the treatment
  • Avoid driving, using machinery, or any activity that requires a high level of alertness - drowsiness and blurred vision are possible side effects of Onglyza
  • Limit your alcohol intake - it can increase your risk of developing low blood sugar and pancreatitis
  • If possible, avoid taking this treatment during pregnancy, only use if clearly needed, and discuss with a doctor. This also applies to women who are breastfeeding
  • This treatment is not for treating type 1 diabetes

How can I buy Onglyza online safely?

You can buy Onglyza online at HealthExpress by completing our quick, free and simple consultation process. All you need to do is answer a few easy questions about your medical history so that our doctors can verify the suitability of this medication. If Onglyza is approved for you, a prescription will be issued to our pharmacy, where they will dispense your medication ready for free next day delivery.

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