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- Menopause
- Elleste Solo
Elleste Solo
Buy Elleste Solo after completing our consultation for HRT
Prices include next-day delivery and prescription
| 3 months £17.99 | 84 tablets |
| 6 months £34.99 | 168 tablets |
Select your treatment after the consultation:
Benefits of product
Reliable menopause support with a simple daily tablet
- Effective relief from hot flushes, night sweats, and insomnia
- Oestrogen-only menopause support for women without a womb
- Helps protect bones and reduce the risk of osteoporosis
- Simple once-daily tablet
- Available in 1 mg & 2 mg estradiol tablets
Elleste products compared
There are 3 different versions of Elleste: Elleste Solo, Elleste Duet, and Elleste Duet Conti. The one that’s right for you depends on your individual circumstances. Here is a helpful table explaining the main differences:
 Elleste Solo |
 Elleste Duet |
 Elleste Duet Conti |
|
|---|---|---|---|
| Type of HRT | Oestrogen-only | Combined oestrogen + progestogen (sequential/cyclical) | Combined oestrogen + progestogen (continuous) |
| Active ingredient(s) | Estradiol hemihydrate | Estradiol hemihydrate & norethisterone acetate | Estradiol hemihydrate & norethisterone acetate |
| Suitable for | Postmenopausal or perimenopausal women without a womb (hysterectomy). | Postmenopausal or perimenopausal women with a womb, including recent bleeding. | Postmenopausal women with a womb who need continuous HRT. |
| Monthly bleed? | No | Yes | No |
How to use Elleste Solo
Start right
If you’re still having regular periods, start on the first day of your cycle. If not, you can start right away.
Take your tablet
Take one tablet at the same time every day and continue without breaks.
Follow your doctor’s advice
Elleste Solo should be taken only as long as necessary. Your doctor will tell you how long to take it for.
Key facts
| Type of medicine | Hormone replacement therapy (HRT) |
| Used for | Menopausal symptoms |
| Active ingredient | Estradiol hemihydrate |
| Works by | Replacing depleted oestrogen levels |
| Effective within | A few weeks, with peak effects felt after approximately 3 months |
| Available as | Tablets |
| Available dosage(s) | 1 mg & 2 mg |
| Usage instructions | Take 1 tablet at the same time every day |
| Packaging | Blister packs containing 28 tablets each (84 total) |
| Manufacturer | Exeltis |
| Generic available? | No |
| Storage | Store below 25°C in the original packaging |
Excellent
4.7
27,162 patients have reviewed our service on Trustpilot
Jon H , 01 Jun
No issues easy process delivering on time.
Jack C , 01 Jun
Fast delivery and good price
Mrs Karen , 01 Jun
On time well packaged.
Ms A , 01 Jun
Fantastic service Always deliver on time Never had any issues Products all quality Help if you should need it Would recommend definitely
Anonymous , 31 May
Very fast reliable service & delivery, would prefer a more private packaging without health express details on it.
Emma B , 31 May
Reliable delivery but lack of communication. Even though an email came through to send that the order had been received and how to store the medication no confirmation comes through to say that the order has been approved. Apart from that im very happy with the service.
Sharon , 31 May
Extremely fast delivery
Kenneth M , 31 May
Easy system to navigate. Speedy and efficient service
Mrs GAYNOR S , 31 May
Health pen arrived without any freezer pack , in just a cardboard box I thought it needs to be kept cold ?
More information about Elleste Solo
About Elleste Solo
What is Elleste Solo?
Elleste Solo is a hormone replacement therapy (HRT) in the form of a daily tablet that relieves symptoms associated with menopause, such as night sweats, hot flushes, and insomnia. It also helps maintain bone density and reduce the risk of osteoporosis. It contains estradiol hemihydrate, an oestrogen that is identical to the one your body naturally produces.
Elleste Solo is an oestrogen-only tablet, meaning it does not contain progesterone. This makes it suitable only if you have had a hysterectomy (a surgery removing the womb). It is available from HealthExpress in 1 mg & 2 mg tablets.
How does Elleste Solo work?
Elleste Solo works by replacing oestrogen your body stops producing during menopause. It does this through its active ingredient, estradiol hemihydrate, which binds to oestrogen receptors to increase hormone levels in the body. With oestrogen levels restored, Elleste Solo eases menopausal symptoms such as hot flushes, night sweats, mood swings, and insomnia, helping women manage menopause more comfortably.
Is Elleste Solo bioidentical to natural oestrogen?
Yes, the active ingredient in Elleste Solo, estradiol hemihydrate, is bioidentical, meaning it is chemically and biologically the same as oestrogen naturally produced by the body. Although it is processed in a laboratory, your body recognises and uses it in the same way as natural oestrogen.
Using Elleste Solo
How do I take Elleste Solo?
Take 1 tablet every day with a glass of water. You can take Elleste Solo at any time of day, just make sure you take every tablet at around the same time to ensure a steady supply of oestrogen.
Each strip of tablets will have arrows to let you know which one to take next. Continue taking tablets every day until the strip is finished, and then start your next one without a break.
Your doctor will let you know how long you should take this treatment for, and you should be prescribed the lowest effective dose to minimise the risk of side effects.
When should I start taking Elleste Solo?
When you start taking Elleste Solo depends on whether or not you still have menstrual periods:
- If you still have regular periods, take your first tablet on the first day of bleeding.
- If you are not having regular periods, you can start straight away.
If you are switching from another oral HRT, start taking Elleste Solo once you finish the one you are currently taking. If switching from another type of HRT (e.g. patches), speak with your doctor about how to switch safely and effectively, as advice depends on what you’re switching from.
How long does Elleste Solo take to work?
Elleste Solo works instantly to replenish oestrogen levels in the body, but it can take up to 3 weeks before you start to notice the effects. It usually takes around 3 months to feel the full effect of oestrogen-only HRTs like Elleste Solo.
Does Elleste Solo cause weight gain?
Some women notice changes in weight while taking Elleste Solo, but it isn’t clear whether this is a result of Elleste Solo directly or of menopause itself. Lower oestrogen levels as a result of menopause have been linked to weight gain due to factors like reduced activity levels, overeating, and changes to metabolism. If this is the case for you, then taking Elleste Solo may help with weight changes by restoring oestrogen levels.
Safety and precautions
Who can take Elleste Solo?
Only women over the age of 18 who have had a hysterectomy (an operation removing the womb) can be prescribed Elleste Solo from HealthExpress. If you still have a womb, you will likely be prescribed Elleste Duet instead, which contains progesterone as well as oestrogen. Progesterone is needed if you have a womb since it helps to protect the womb lining from thickening, which can increase the risk of endometrial hyperplasia and womb cancer.
Do not take Elleste Solo if you have:
- a womb and are not taking a progestogen alongside Elleste Solo
- an allergy to estradiol hemihydrate or any other ingredient found in this medicine
- ever had breast cancer
- ever had a cancer sensitive to oestrogens, such as endometrial cancer
- unexplained vaginal bleeding
- excessive thickening of the womb (endometrial hyperplasia) that is not being treated
- ever had a blood clot or a disorder affecting clotting
- recently had a disease caused by a blood clot in the arteries, such as heart attack or stroke
- ever had a liver disease and your liver function tests have not returned to normal levels
- porphyria, a rare inherited blood disease
Make sure you tell your doctor about any health issues you have and all medicines you take in your consultation so they can ensure safety when prescribing treatment.
What are the most common side effects of Elleste Solo?
Elleste Solo can cause side effects, but not everyone will get them. Tell your doctor if you experience any side effects as a result of taking this medicine.
The most common Elleste Solo side effects include:
- feeling sick
- abdominal pain
- headache
- breakthrough bleeding
- changes to your period
- vaginal bleeding, including spotting
- weight changes
- swelling of the legs
- tender or enlarged breasts
- changes in mood
- decreased or increased libido (sex drive)
- rash or itching
This is not an exhaustive list. For a full list of Elleste Solo’s side effects, consult the patient information leaflet.
How safe is Elleste Solo?
Elleste Solo is safe provided you are prescribed treatment from a licensed healthcare provider like HealthExpress. Elleste Solo was approved for use in the UK in 1994, meaning it has a long track record of clinical use and monitoring.
If you still have a womb, you will either be prescribed a combined HRT like Elleste Duet that contains progesterone and oestrogen, or a progestin alongside Elleste Solo.
