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Testosterone Replacement Therapy (TRT)

Know your levels. Then decide.

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  • Diagnosis first approach
  • Assesses suitability for TRT
  • Personalised treatment plan

Our TRT service is coming soon

Interested in TRT? Leave your email and we'll let you know when you can get started.

No commitment—just an email when we launch.

Step 1

Before considering treatment, we find out if you actually need it. All it takes is a simple at-home blood test.

Recognised symptoms of TD
Recognised symptoms of TD
Sound familiar?

These symptoms might have a clinical explanation —
and a clinical solution.

Do these sound familiar?

Recognise the symptoms

  • Low energy

    Persistent fatigue affecting daily activities

  • Reduced muscle mass

    Difficulty building muscle despite exercise

  • Decreased libido

    Reduced sex drive and performance issues

  • Brain fog

    Difficulty concentrating and memory problems

  • Mood changes

    Irritability, depression, and emotional instability

  • Weight gain

    Increased body fat, especially around the midsection

Below 15 nmol/L

Not everyone with these symptoms has low testosterone. Blood testing is the only way to know for sure. If your test shows levels below 15 nmol/L, we help you take the next step.

Testosterone Deficiency

A medical diagnosis, not an inevitable decline.

Testosterone levels by age (nmol/L)
Testosterone chart
  • Testosterone level
  • Clinical threshold (12 nmol/L)

Testosterone Deficiency (TD) is a recognised medical diagnosis, not a natural consequence of getting older that you simply have to accept. When testosterone falls below a clinical threshold, it can affect multiple systems in the body, including energy, mood, body composition, libido, and cognitive function.

And it's more common than most men realise. Studies suggest around 1 in 4 men over 30 have testosterone levels that fall below the normal range, the majority of which go undiagnosed.

TD is not the same as the gradual testosterone decline that comes with age. It's a deficiency which can be treated.

Testosterone Replacement Therapy

Restoring what your body is no longer producing.

Testosterone levels: before & after TRT (nmol/L)
Testosterone levels before and after TRT. Untreated testosterone sits flat at around 10 nmol/L, below the 12 nmol/L clinical threshold. Once TRT starts at about six months, levels rise into the 20 to 28 nmol/L normal range and stay there.
  • Without TRT
  • With TRT
  • Clinical threshold

TRT replenishes testosterone to levels your body should naturally maintain. It's not performance enhancement, it's restoring a hormone to its normal physiological range, under medical supervision, in men who have been clinically confirmed to be deficient.

Treatment comes in the form of injections or gels, all with the same goal: bringing testosterone back into a normal range and keeping it there consistently.

TRT is only appropriate when testosterone deficiency has been confirmed through blood testing. That's exactly why we start there.

Clinical self assessment

Are your symptoms caused by low testosterone?

Question 1 of 10

Do you have a decrease in libido (sex drive)?

Question 2 of 10

Do you have a lack of energy?

Question 3 of 10

Do you have decreased strength and/or endurance?

Question 4 of 10

Have you lost height?

Question 5 of 10

Have you noticed a decrease in "Enjoyment of life"?

Question 6 of 10

Are you sad and/or grumpy?

Question 7 of 10

Are your erections less strong or do you struggle to maintain them?

Question 8 of 10

Have you noticed a deterioration in your ability to exercise?

Question 9 of 10

Are you falling asleep after meals?

Question 10 of 10

Has there been a recent deterioration in your work performance?

Your results suggest possible testosterone deficiency

Based on your responses, your symptoms could be linked to low testosterone. The next step is a simple blood test to check your levels properly.

Start with a blood test -

Your results don't indicate a likely deficiency

Based on your responses, your symptoms don’t strongly suggest testosterone deficiency at this stage. If your symptoms change or worsen, it’s worth speaking to your GP.

This questionnaire is a screening tool, not a diagnosis. A blood test is required to confirm low testosterone.

The process

Four steps. No guesswork.

At-home testosterone blood test kit
1

At-home blood test

Start with a simple at home test. Measures 5 biomarkers to see whether low testosterone is the cause of your symptoms.

  • Total testosterone
  • Free testosterone
Results in 2-3 working days
Phone showing blood test biomarker results
2

Blood test to confirm

If levels are low, you take a 46-biomarker blood test at a clinic or via a nurse to confirm your diagnosis in more detail.

  • Full testosterone panel
  • Kidney and liver
£79.99
Results in 2-3 working days
Man in an online doctor consultation
3

Doctor consultation

Next, we invite you to book a free online consultation with one of our doctors to discuss your results and treatment options.

  • 30 minute online consult
  • Treatment and monitoring plan
Free
Daily slots available
Testosterone treatment medication
4

Monthly treatment

Your prescription is delivered monthly. We include regular blood tests to check your levels and adjust treatment if needed.

  • Free discreet delivery
  • Blood tests at 3, 6 & 12 months
Prices from £74.99/month
Ongoing care
Type of treatment

Treatment planned around you

From £74.99 a month

Don't worry about choosing right now.
In your consultation, one of our doctors will clearly explain your treatment options, along with their pros and cons. You can then choose the type that suits you best.

Injections Image

Injections

  • Testosterone injected directly into the muscle
  • Self-administered every 3 weeks
  • All follow up blood tests included
  • All doctor consultations included

Show the pros and cons

Benefits

  • Highest bioavailability of all TRT forms
  • No daily application, less frequent dosing
  • Predictable testosterone levels
  • Well researched, clinically established protocol

Considerations

  • Requires self injection
  • Levels can peak and trough between doses
  • May cause brief soreness at injection site
  • Not suitable for those with a fear of needles

Show treatments

  • Sustanon
  • Testosterone Enantate
  • Testosterone Cypionate
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Gels

  • Testosterone gel applied daily to the skin
  • Consistent daily hormone delivery
  • All follow up blood tests included
  • All doctor consultations included

Show the pros and cons

Benefits

  • No needles, the gel is applied directly to the skin
  • Easy to incorporate into a morning routine
  • Dose easily adjusted by your doctor

Considerations

  • Must remember to apply daily
  • Risk of transferring testosterone to others via skin contact
  • Must dry completely before dressing
  • May cause skin irritation at application site

Show treatments

  • Testavan
For fertility preservation
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Preserve fertility

Clomifene (tablets)

  • This is an off-label treatment
  • Stimulates your own testosterone production
  • Can be combined with injections or gel
  • All blood tests and consultations included

Show the pros and cons

Benefits

  • Preserves fertility, unlike testosterone injections or gels
  • Can be combined with TRT injections/gels if our doctor recommends it
  • No needles, no daily application
  • Dose adjusted gradually based on your bloodwork and symptoms

Considerations

  • Generally less effective for symptom relief than injections or gels
  • Off-label use, not licensed specifically for this
  • Takes several weeks of dose titration before reaching full effect
  • May cause hot flashes, mood changes, headaches, or visual disturbances

Show treatments

  • Clomifene (Clomid)

Note: Decisions about treatment are for both the prescriber and the person to jointly consider during the consultation. However, the final decision will always be the prescriber’s.

Why HealthExpress

Doctor-led, diagnosis-first approach

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300K+CONSULTATIONS IN UK

Treatment that’s right for you

TRT isn't right for everyone. We only prescribe when blood tests confirm your symptoms are caused by TD. If suitable, one of our doctors with experience in hormone health will discuss your options so your plan is tailored to you.

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15+ yearsexperience

Quick but careful assessment

We aim to give you clear answers about whether your symptoms are related to low testosterone within a few weeks. But we carefully assess your symptoms alongside blood test results before recommending any treatment, so you can decide with confidence whether TRT is right for you.

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Ongoing support included

You're supported at all stages throughout your treatment. Regular blood tests and follow-up reviews are included to keep everything on track, and our dedicated support team is always available if you have questions.

A step by step guide

What to expect

Start with a blood test
  • 1st day

    • You’ve taken your first dose today.
    • It’s normal not to feel anything straight away. Your body needs time to respond.
    • Take a moment to notice how you’re feeling now: your energy, mood and libido, so you can look back and see changes clearly.
  • 1st week

    • You might start to notice subtle shifts, perhaps a slightly better mood or improved sleep.
    • Energy can feel a little uneven at first. That’s normal while your levels adjust.
    • Focus on overall trends rather than day to day changes.
  • 1st month

    • By around week four, many men feel more steady energy and clearer focus.
    • Libido often begins to return gradually.
    • Mood can feel more stable now, with fewer dips and less irritability.
  • 3rd month

    • By now, things usually feel more settled.
    • Physical changes may become more noticeable, for example, improved strength or a change in body composition.
    • Mental clarity often improves significantly.
    • A follow-up blood test is done here to help us fine-tune your dose if needed.
  • 6th month

    • Benefits are typically more consistent: steady energy, stable mood and restored libido.
    • Physical changes continue to develop over time.
    • Ongoing monitoring with blood test at 6 months helps keep everything safe and on track.
Start with a blood test
Frequently asked questions

More info about TRT

TRT

What is TRT and TD?

Testosterone Deficiency (TD) is a medical condition where the body does not produce enough testosterone. This can lead to symptoms such as low energy, reduced libido, low mood, and difficulty building or maintaining muscle.

Testosterone Replacement Therapy (TRT) is a treatment used to restore testosterone levels back to the normal range. It may help improve symptoms when TD has been confirmed through blood tests and a clinical assessment.

TRT is only prescribed after a proper diagnosis, and ongoing monitoring is required to ensure treatment remains safe and effective.

Who is eligible for TRT?

We assess eligibility based on current clinical best practice and medical evidence.

This includes: Testosterone levels below the normal range (typically < 15 nmol/L) · Symptoms consistent with low testosterone

As testosterone levels can fluctuate, a second test is required to confirm the diagnosis.

We also review additional biomarkers, your symptoms, and your medical history to make a balanced treatment decision that's personalised to you.

Is TRT safe?

When prescribed appropriately and monitored regularly, TRT can be a safe and effective treatment for men with confirmed testosterone deficiency. Ongoing blood tests are required to ensure levels remain within a healthy range.

Can TRT affect fertility?

Yes, TRT can reduce sperm production and may not be suitable for men who are planning to conceive. If fertility is a concern, alternative approaches may be discussed during your consultation.

Assessment

Why do I need a second (venous) blood test?

Testosterone levels naturally fluctuate. A venous test confirms whether levels are consistently low and allows us to assess related hormones and safety markers before treatment is considered.

What testosterone level qualifies for treatment?

Testosterone levels below 15 nmol/L are generally considered below the normal range. To diagnose Testosterone Deficiency, levels must be consistently low on two separate tests, alongside symptoms. Treatment decisions are based on your blood results, symptoms, and medical history. Our doctors review each case individually before prescribing.

How do I collect the blood samples?

Our at-home test kits are designed to be simple and easy to use. Each kit includes clear step-by-step instructions.

Finger prick test: Use a small lancet to collect a blood sample from your finger. Download the full instructions or watch the instruction video.

Arm device: Use a needle-free device applied to your upper arm to collect a blood sample. Download the full instructions or watch the instruction video.

If your sample cannot be processed, you will need to purchase a replacement kit. Please contact our customer service team to arrange this.

When will I receive my results?

Once the lab has received your sample, you can expect your results within 2-3 working days

What happens if my sample fails and is rejected by the lab?

Venous blood tests: If your venous sample cannot be processed, please contact our customer service team and we'll help arrange a retest.

At-home test kits: If your sample is rejected for any of the below reasons, you will need to purchase another test:

  • Unlabelled – no label attached to the sample
  • No form – no completed lab form included
  • No sample – no usable sample provided
  • Insufficient – sample container was not filled to the level specified
  • Leaked – sample was not packaged correctly
  • Too old – sample was not posted shortly after collection.

If your finger prick sample is haemolysed (blood damaged during collection) or clotted, we will provide one free retest.

In all cases, please contact our friendly customer service team to arrange for a retest. More information is available in our Terms and Conditions.

Treatment

What treatment options do I have?

TRT is typically prescribed as either injections or gels. Each option has its own benefits, and the right choice depends on your lifestyle, preferences, and medical needs.

During your consultation, your doctor will explain the options in detail and recommend the most suitable treatment based on your blood results and health history.

What side effects can occur?

Possible side effects may include increased red blood cell count, acne, fluid retention, or changes in mood. Current evidence does not show that properly monitored TRT increases prostate cancer risk. Your doctor will assess your cardiovascular health and prostate markers before and during treatment, ensuring treatment remains safe and appropriate for you.

How long does it take for TRT to work?

Some effects of TRT can be noticed within a few weeks, but full benefits may take several months. The timeline varies depending on your baseline testosterone levels, the treatment type, and your overall health. Regular follow-ups are important to monitor your progress and adjust treatment where needed.

Is TRT a lifelong treatment?

TRT is often a long-term treatment, but this varies from person to person. Some men choose to continue treatment long term to maintain symptom improvement, while others may stop if their situation changes.

You can stop treatment if needed, but this should only be done under medical supervision. If treatment is stopped, testosterone levels typically return to your natural baseline.

Your doctor will discuss what to expect before starting treatment and will review your therapy regularly to ensure it remains right for you.

Medically reviewed by Dr. Anup Jethwa GMC, MBBS MPharm MRCGP Written by our editorial team Last reviewed 08-10-2026
Already diagnosed?

Already on TRT? Continue your treatment with us.

If you've already been diagnosed with low testosterone and are currently receiving TRT elsewhere, you can move your ongoing care to us.

The process is straightforward and designed to get you set up with minimal disruption to your treatment.

  • Tell us about your diagnosis and treatment so far
  • Book your Advanced TRT blood test - this ensures your doctor has a current, complete picture of your health
  • Book a free video consultation with one of our doctors
Start your transfer

A doctor who knows your history

We start with a full picture of your health — your diagnosis, your current medication, how you're responding — then we run a comprehensive blood test before your consultation. No shortcuts, no guesswork.

Monitoring included — not an afterthought

Regular blood tests are built into your plan and included in the price. If your levels shift or your dose needs adjusting, we catch it, you don't have to chase it.

Seamless, no disruption

Consultation, prescription, monthly delivery, all managed online with expert personal care. Your free video consultation is booked around you, with appointments available every day.

Experts

Our team supports you every step of the way

Support team

Support team

Our friendly support team
provides fast, discreet, and
knowledgeable help.