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Femseven Patches

Buy Femseven after completing our online consultation for menopause symptoms

standard dose
50mcg
3 months 12 patches (£54.99)

Prices include next-day delivery and prescription

3 months £54.99 12 patches
6 months £89.99 24 patches

Select your treatment after the consultation:

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Start your consultation in the next 6h and 31min to receive your order Friday, 24 Apr
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An overview

Benefits of product

Close-up of a woman in a striped top applying a patch to her lower abdomen

Steady menopause relief with discreet once-weekly patches

  • Eases symptoms of menopause like hot flushes and night sweats
  • Discreet once-weekly patch applied to a non-visible area
  • Typically for women without a womb (hysterectomy)
  • Contains body-identical oestrogen (estradiol)
  • Available as 50 mcg, 75 mcg, and 100 mcg patches
Practical info

How to use Femseven Patches

The midsection of a woman in gym clothes holding her thigh with both hands

Prepare the skin

Choose a clean, dry, hairless area of skin below the waist, ideally on the thigh or buttocks.

An elderly woman smiling and holding up a transdermal patch

Apply the patch

Peel off the protective layer and press the patch firmly onto your skin, smoothing out any wrinkles or air bubbles.

A calendar with a red pin stuck into one of the dates

Replace weekly

Wear each patch for 7 days before removing it and applying a new one. Rotate application sites to avoid skin irritation.

Quick overview

Key facts

Type of medicine HRT (hormone replacement therapy)
Used for Menopause symptoms
Active ingredient Estradiol hemihydrate
Works by Restoring oestrogen levels that are reduced during menopause
Effective within A few weeks to 3 months
Available as Transdermal patches
Available dosage(s) 50 mcg, 75 mcg, 100 mcg
Usage instructions Apply once weekly to skin below the waist
Packaging Box containing 4 patches
Manufacturer Theramex
Generic available? No
Storage Store below 30°C in the original packaging
Independently collected reviews Service reviews
Excellent 4.7 26,973 patients have reviewed our service on Trustpilot
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Stuart D , 22 Apr

product as described, good price and promptly dispatched.

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Mr Parker , 22 Apr

My original card was compromised. My new card number was accepted without problems. I then received my medication promptly.

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David K , 21 Apr

next day delivery always arrives on time

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Jennifer A , 21 Apr

Always fast and reliable service

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Richard F , 20 Apr

Good selection of products to choose from after the consultation period, the questions do seem thorough to reach a conclusion. Th product I chose was delivered fast and with fantastic communication, I wouldn’t hesitate to recommend these people. Thank you to all .

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Febiola L , 20 Apr

Easy to order and smooth delivery throughout.

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Sally C , 20 Apr

Easy to order Quick delivery

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Mrs fredericks , 20 Apr

Order arrived late. Ice pack had completely melted.

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Mark , 20 Apr

I had a lot of trouble with reordering from the website. At the final stage the site was endlessly buffering. I accessed my account again from a different web browser and the same thing happened. The online chat wasn’t much help, advising me to delete my history and try again - no joy. Then I was asked to call the helpline. When I did this I was informed there was no one available and asked to leave a message, which I did. No one called back. It was only on the second occasion that I got through to a person who confirmed my order. In the days following I was bombarded by electronic emails telling me I had an incomplete order (which I didn’t) and asking if a needed help (!)

Your questions answered

More information about Femseven

About Femseven

What is Femseven?

Femseven is a hormone replacement therapy (HRT) patch for postmenopausal women who are experiencing symptoms caused by lower oestrogen levels after menopause.

The patch is applied to the skin once a week and helps relieve symptoms such as hot flushes, mood changes, and sleep difficulties. It provides discreet, ongoing support for women who no longer have a womb.

At HealthExpress, we offer Femseven in 50 mcg, 75 mcg, and 100 mcg doses, so you can find a patch that suits you.

What’s the difference between Femseven and Femseven Conti?

Femseven comes in two main forms: the standard Femseven patch and Femseven Conti. The key difference is that Femseven is an oestrogen-only patch, whereas Femseven Conti combines oestrogen with a progestogen (levonorgestrel).

Because Femseven doesn’t contain a progestogen, Femseven patches are generally more suitable for women who have had a hysterectomy. If you still have a womb, you’ll also need to take a progestogen to protect the womb lining during treatment with Femseven. This prevents the womb lining from thickening, which can increase the risk of womb cancer.

How does Femseven work?

Femseven works by releasing estradiol hemihydrate through the skin, which then binds to oestrogen receptors. Estradiol is a body-identical oestrogen that replaces levels of the hormone lost during menopause.

With hormone levels restored, symptoms usually ease, helping you feel more like yourself again.

How effective is Femseven?

Clinical studies have found Femseven to be a well-tolerated and effective way to treat menopause symptoms. In particular, it effectively reduces symptoms like hot flushes and night sweats.

One study involving 19 postmenopausal women over 60 found that cognitive health significantly improved after treatment with Femseven. This included things like reaction time, spatial working memory, and mood. In general, most women involved in this study found that symptoms of menopause improved after at least 12 weeks using Femseven.

Using Femseven

How do I apply Femseven patches?

Follow these instructions when putting on Femseven patches:

  1. Choose a dry and hairless part of skin on the thigh or buttocks. Make sure the area will not be rubbed too much by clothing.
  2. Remove the patch from its pouch.
  3. Peel off half of the protective layer. Do not touch the sticky side.
  4. Apply the sticky part to your skin.
  5. Remove the other side of the protective layer, sticking the patch to your skin as you do so.
  6. Press the patch onto your skin for at least 30 seconds.

Change application sites weekly to avoid skin irritation. If you forget to apply a patch, apply it as soon as possible and your next one at the usual time. Do not use 2 patches at the same time.

How often should I use Femseven?

Each Femseven is worn for 7 days. After a week, remove the patch by peeling it off from one corner, and apply a new one to a different area of skin on the thigh or buttocks.

How long does Femseven take to work?

Femseven starts supplying oestrogen immediately after you attach it. It can however take a few weeks or up to 3 months for you to notice an improvement to your symptoms.

What dosages are available?

Femseven patches are available in 50 mcg, 75 mcg, and 100 mcg doses. This refers to the amount of oestrogen released every 24 hours.

The 50 mcg patch is the lowest effective dose and is usually prescribed first.

If your symptoms are not adequately controlled after around 3 months, your doctor may review your treatment and consider increasing the dose to 75 mcg, and then 100 mcg if needed.

Safety and precautions

Who can and cannot take Femseven?

To be prescribed Femseven, you usually need to be a woman going through menopause who no longer has a womb. This is typically due to a hysterectomy.

If you still have a womb, you may be prescribed Femseven alongside a progestogen, but most women in this situation are offered a combined patch such as Femseven Conti instead. Your doctor will advise what’s safest for you.

Do not take Femseven if you have:

  • an allergy to estradiol or any other ingredient found in this medicine
  • cancer that is sensitive to oestrogens
  • unexplained vaginal bleeding
  • untreated endometrial hyperplasia (excessive thickening of the womb lining)
  • ever had a blood clot
  • a blood clotting disorder
  • porphyria (a rare inherited disease)

What are the most common side effects of Femseven?

HRT patches are generally tolerated better than oral treatments, but Femseven can still cause side effects.

The most common Femseven side effects include:

  • skin reactions (itching, redness, swelling)
  • headache
  • breast discomfort

For a full list of Femseven’s side effects, consult the patient information leaflet.

How safe is Femseven?

Femseven is considered safe for most women, provided it is prescribed by a licensed healthcare professional. It was approved for use in the UK in December 2005, and since then has been a trusted product for thousands who rely on it for effective HRT treatment.

However, as with all HRT medicines, it can pose some risk. You should take special care if you still have a womb or you have a condition that makes you more likely to get a blood clot. Speak with your doctor if you’re unsure about the safety of treatment with Femseven.

Medically reviewed by Dr. Caroline Fontana Written by our editorial team Last reviewed 01-04-2026
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