• Replenishes oestrogen loss
  • Reduces menopausal symptoms
  • Tolerable HRT tablets

Premique Low Dose is a hormone replacement therapy (HRT) used to help treat symptoms associated with menopause that is caused by a drop in oestrogen. You can buy Premique HRT treatment safely online at HealthExpress. All you need to do is start one of our completely free and confidential online consultations. This will be checked by one of our partner doctors. Your prescription is then handed to the pharmacy who will prepare our HRT tablets for free next day delivery straight to your door when you order before 4.30pm.

Easy & convenient

No appointments or wait time

Free Consultation

Our partner doctors will assess your medical history

Confidential Service

Private payment and discreet packaging

Prescription Medications

Dispensed same day by UK registered pharmacies

What is Premique?

Premique is a hormonal replacement therapy (HRT) taken in the form of a tablet. It is available in the dosage of 300mcg / 1.5mg. It's a period-free HRT treatment meaning that you don't have a monthly bleed, but contains two active ingredients, namely conjugated oestrogens and progestogen, making it suitable for women who have not had a hysterectomy. It helps to replace the depleted oestrogen levels in the body, alleviating problematic symptoms associated with the menopause and is available in this lower dosage suitable for women who are prone to side effects.

How does Premique work?

Premique contains the synthetic hormones conjugated oestrogens and medroxyprogesterone acetate. Conjugated oestrogens are natural oestrogens, meaning that they cause the body to respond in a very similar way to the oestrogen that is naturally produced. In general, conjugated oestrogen is considered better for HRT in comparison to the artificial oestrogens that are used in contraceptives.

By taking Premique, oestrogen levels can be kept as close as possible to normal to help alleviate menopausal symptoms. However, in women with a uterus, taking oestrogen can increase the risk of endometrial cancers.

What are the benefits of Premique?

Menopause can result in a number of uncomfortable conditions and symptoms; this is largely because the body doesn't produce female sex hormones like it used to. Premique hormone replacement therapy works effectively to reduce these symptoms and provide some relief for the user. A drop in oestrogen in particular is to blame for the most bothersome symptoms experienced by women after menopause. Menopause can cause women to experience night sweats, hot flashes, vaginal dryness and a loss in bone density that could increase a woman's risk of developing osteoporosis.

Premique also contains progestogen, which means that women who have experienced menopause but have not had a hysterectomy can use this medication to reduce the risk of womb cancers as a result of oestrogen supplements.

How to use Premique?

Premique tablets should be taken daily for 28 days, ideally at the same time. Each pack contains the days of the week to ensure that you can keep track of whether you've taken your pill or not. There should be no break between the packs for consistent results.

When you first start using this treatment, you'll most likely be prescribed the lowest dose first to ensure that you don't experience side effects and that you benefit from the medication, as you should.

What if I miss a tablet?

A tablet should be taken as soon as you remember, and the therapy should carry on as usual. If more than one tablet has been forgotten then only the most recent dose should be taken, never double dose to make up for a missed tablet. Also be aware that missed pills may cause breakthrough bleeding.

Precautions/interactions when taking Premique?

Premique will normally be prescribed to women over the age of 18 who have not had a hysterectomy and who are experiencing menopausal symptoms. Before deciding to buy Premique, there are a number of precautions that should be considered.

  • Premique should be used with caution if you have a history of breast cancer (or benign breast lumps), asthma, depression, or gallbladder disease.
  • Should not be taken if you have had stroke or coronary heart disease
  • This treatment should also be used with caution if you are dealing with conditions that make you more vulnerable to blood clotting, liver disease, diabetes, high blood pressure, obesity, epilepsy, depression, or undiagnosed vaginal bleeding
  • Premique shouldn't be taken if you have had a stroke or heart attack recently, or if you are intending to use this treatment during pregnancy or whilst breastfeeding.

HealthExpress will only approve consultations for women who have already been recommended this hormone replacement therapy treatment by their regular doctor and are seeking a repeat prescription.

What dosages are available for Premique?

Premique comes in one strength from HealthExpress; Premique Low Dose. Premique Low Dose tablets each contain 300 micrograms of conjugated oestrogen (equine) and 1.5 milligrams of medroxyprogesterone.

What are the side effects of Premique?

Side effects of oestrogen and progestogen treatments such as these may include:

  • Headaches
  • Backaches
  • Indigestion
  • Fluid retention
  • Mood changes or changes in sex drive

Luckily most of these can be avoided by ensuring that you exercise enough, eat healthily and take this HRT treatment with meals.

If you experience anything worse or these effects are bothering you, it's important that you speak to your doctor, although most doctors will be able to monitor you effectively enough while using this medication to ensure that you are safe while using it.

How can I buy Premique online safely?

You can buy Premique or other hormone replacement therapy medications safely and securely online from HealthExpress. However, we advise that you only do so if you are already using this treatment and you've been recommended it by your doctor. Simply complete a quick, free, and simple online consultation, providing as much information as possible, so that our partner doctor will be able to assess your eligibility for a prescription. If your consultation is approved you'll be able to complete your order and your treatment will be dispensed and sent directly from our pharmacy straight to you via our next day or same-day delivery service.

Dr Hilary Jones Independent Medical Adviser

Still not sure? Take our free consultation to find the right treatment for you.

Start Free Consultation

Review healthexpress on

Service ratings
5 4.8
4,367 patients have rated our service
Product ratings
Strip front and back view
25 patients have reviewed Premique

Reachable and friendly Customer Service

Customer Service Online now: Mon-Fri 8:00am - 5:30pm

All-inclusive service - No hidden fees

All prices include shipping & prescription

Next day delivery

Guaranteed to all orders before 4:30 PM

All reviews for Premique

Excellent 20 Aug

Product Review:excellent service and timing will use again

Service Review:

Excellent 28 Jul

Product Review:It's a lifesaver for me. Makes me feel like me again

Service Review:

Excellent 26 Jun

Product Review:This product has been hard to get in the past so I was very pleased to be...

Service Review:

Excellent 02 Jun

Product Review:Relieved to be able to obtain this product as no longer available from G.P

Service Review:

Excellent 23 Apr

Product Review:This is a good product I've used before. Responsibly provided at the lowest...

Service Review:

Excellent 07 Oct

Product Review:Your service is very friendly and helpful. Thank you very much.

Service Review:Your service is very friendly and helpful. Thank you very much.

See all reviews