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Buy Nitrofurantoin online for effective cystitis treatment

  • MacroBID 100mg (nitrofurantoin) prolonged-release 14 capsules
4.8 477 patient reviews on Trustpilot
100mg (modified release)
6 Capsules (£14.99)

Prices include next-day delivery and prescription

6 Capsules £14.99

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Please note, this treatment is currently only available from HealthExpress for women. If you are a man and showing symptoms of a urinary tract infection (UTI), you should visit your GP or GUM clinic. They will be able to rule out more serious underlying causes.

More information about Nitrofurantoin

What is Nitrofurantoin?

Nitrofurantoin is an antibiotic prescribed to treat urinary tract infections (UTIs), specifically cystitis. It contains the active ingredient of the same name.

Nitrofurantoin is also available as a branded version, sold under different names, such as MacroBID. However, if you buy Nitrofurantoin online from HealthExpress, it has identical properties and effects as MacroBID - coming in the form of 100mg modified-release (MR) capsules or tablets.

You should only take this medication if you have been prescribed it by a doctor (this includes our online prescription). Taking antibiotics unnecessarily will cause more harm than good lead to increased antibiotic resistance.

Please note, this treatment is not available online to men. This is because UTIs are more difficult to diagnose in men and can indicate more serious conditions. If you are male, you should visit your GP or local GUM clinic.

If you are pregnant or trying to conceive, you should ask your doctor about more suitable treatment.

How does Nitrofurantoin work?

When you take Nitrofurantoin, the active agent is absorbed by the body and eventually concentrates in your urine - this is why it is especially effective at treating UTIs.

As an antibiotic, Nitrofurantoin works by damaging the DNA of the bacterial cells so they are unable to repair or reproduce. It prevents them from creating a necessary protein. Consequently, your immune system can better fight the infection.

Please note, you must complete the prescribed course, even if symptoms clear early. Due to the way antibiotics work, the infection can return if prescribing instructions are not followed.

If you are uncertain about the length of your course, please consult your doctor or patient information leaflet (PIL).

How do I take Nitrofurantoin?

For full instructions, please consult the patient information leaflet (PIL).

  • tablets should be taken whole - do not crush or split them
  • tablets should be taken with meals or milk - to help you absorb the medication and avoid feeling nauseous

To ensure your infection is cleared completely, you should finish your course of treatment, even if you do start to feel better before the full time of treatment.

The antibiotic has different treatment lengths for men and women, as follows:


You should take a 100mg (MR) capsule twice a day, for three days.

Alternatively, if you are prescribed the 50mg dosage, you should take tablets four times a day for three days.

If symptoms persist beyond three days, you can continue to take the medication for up to seven days, or until the symptoms resolve. If symptoms persist beyond seven days, please seek immediate medical advice.


Please note, if you are male, you cannot be prescribed this medication online. You should contact your regular doctor for an in-person diagnosis.

Most UTIs affect the bladder and the urethra, which is the tube that drains urine from the bladder. UTIs are a very common infection for women, but rare for men.

When a man develops a UTI, it is usually considered complicated and more likely to spread to the kidneys.

If diagnosed and prescribed in-person, men should take a 100 mg (modified release) capsule twice a day for seven days to clear the infection. Alternatively, take a 50mg tablet four times a day for seven days.

If symptoms persist beyond seven days of treatment, please seek immediate medical advice.

How long does Nitrofurantoin take to work for UTIs?

Mostly, that depends on the length of a course. If prescribed for three days, you should expect the infection to noticeably improve after that time, and then it should be completely clear by seven days. If prescribed for seven days, the infection should have gone by the end of the course. As mentioned, if it persists, inform your doctor - you may need more potent treatment.

What are the possible side effects of Nitrofurantoin?

For a full list of side effects, please read the patient information leaflet. You will find this included with your order.

You should take this medication with food to minimise feelings of nausea.

Nitrofurantoin might cause urine to turn dark yellow or brown in colour, however, this is normal and is only temporary.

Other common side effects include:

  • vomiting
  • loss of appetite
  • stomach pain
  • diarrhoea
  • dizziness
  • headache

If you experience any breathlessness or difficult breathing after starting this treatment, please seek immediate medical attention.

You should report any unlisted side effects to your doctor. You should also inform your doctor if any reactions are unpleasant or long-lasting.

What precautions should I take?

There are some precautionary measures you need to take into consideration before using Nitrofurantoin for the first time.

Before using this medication you should consult your doctor about any allergies or medical conditions as well as your medical history.

If any of the following apply to you, you should seek other treatment:

  • you have a kidney condition
  • you are pregnant (especially if in the final stages)
  • you have porphyria
  • you or a child you are breastfeeding has a G6PD deficiency
  • you have an allergy to any of the ingredients of this medication

Please note, Nitrofurantoin can cause bacterial vaccines to not work as effectively. Do not schedule vaccinations during your course of treatment.

You should avoid alcohol when using this medication. Instead, drink plenty of water to help flush the bacteria out.


This medication cannot be prescribed online to women who are pregnant. You should contact your doctor to explore different options.

Can you drink on Nitrofurantoin?

You should avoid alcohol when using this medication. Instead, drink plenty of water to help flush the bacteria out.

Though the alcohol won’t actually affect the way Nitrofurantoin works, it will impede how well your body can fight infection.

Can I buy Nitrofurantoin online?

To buy Nitrofurantoin online, you need to fill out a short medical questionnaire which our team of registered doctors will review. If the treatment is right for you, our doctors will issue a prescription to our pharmacy.

We will then send your order with a next-day delivery service.

Our doctors are all based in the UK and our service has all the relevant and mandatory safety certificates. These can be viewed at the very bottom of this page.

Note: Decisions about treatment are for both the prescriber and the person to jointly consider during the consultation. However, the final decision will always be the prescriber’s.

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Nitrofurantoin reviews
Excellent 4.8 477 patients have reviewed Nitrofurantoin on Trustpilot
Featured reviews
  • Definitely the cheapest option with next day delivery I could find. Product is the same as everywhere else but the ease of using this service makes it better suited for busy lifestyle and I saved quite a bit on my treatment as well. Works for me.

    Miss Agata
  • Just the right thing I needed to wipe of a stubborn UTI.Came packaged well too.100% satisfied!

    Gwyneth Mzingwane Chimombe
  • Over the counter medication doesn't seem to work for me but a course of Nitrofurantoin does the trick. Comes highly recommended as a quick fix for cystitis.

    Sandy Febvre
  • I would like to thank Healthexpress, for the speedy medicine, which arrived as promised. I would have no worrys in contacting yourselves in the near future. Many Thanks.

  • Got this for a uti. Still have one left to take but so far they have really helped me get rid of the symptoms that was bothering me so much. Thumbs up from me.

  • I've nearly completed the course of treatment and am delighted with the results. As a bonus, the meds cleared up a nasel infection I had alongside my grumbling UTI. THANKS A+++

11 May

Good product for what I needed. And it worked fast

08 May

Effectively cleared up my uti

bernadette p
08 May

Great product sorted out my uti.

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