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Mounjaro price increase wegovy switch

Wegovy vs Mounjaro

Comparison Wegovy Mounjaro
Avg. weight loss Up to 21%* Up to 20%*
Active ingredient Semaglutide Tirzepatide
Type Weekly injection Weekly injection
Dosing schedule Increase, decrease or maintain monthly Increase, decrease or maintain monthly
Oral contraceptives No impact May reduce effectiveness
Injection site reactions** 1.4% of patients 3.2% of patients
Licensed to reduce cardiovascular risk Yes No

*Effectiveness: In clinical trials, Wegovy (semaglutide) users lost up to 17% with the 2.4 mg dose (STEP 1), and up to 21% with the upcoming 7.2 mg dose (STEP UP). The highest dose of Mounjaro (tirzepatide) led to an average weight loss of around 20% (SURMOUNT-1).

**Injection site reactions: In clinical trials, mild reactions like redness, itching or discomfort at the injection site were reported less often with Wegovy (1.4% in STEP phase 3) than with Mounjaro (3.2% in SURMOUNT-1).

Find your Wegovy dose

Switching doesn’t mean starting over. We’ll match your current Mounjaro dose
to the most suitable Wegovy dose so your progress stays on track.

Dosage Guide Img

Select your current Mounjaro dose:

Wegovy dose options:

Equivalent Icon Equivalent dose: 0.25mg
If you’ve experienced side effects on Mounjaro, consider starting on a lower Wegovy dose to help reduce the chance of new side effects when switching.

Wegovy dose options:

Equivalent Icon Equivalent dose: 0.5mg Step down Icon Step-down dose: 0.25mg
If you’ve experienced side effects on Mounjaro, consider starting on a lower Wegovy dose to help reduce the chance of new side effects when switching.

Wegovy dose options:

Equivalent Icon Equivalent dose: 1mg Step down Icon Step-down dose: 0.5mg
If you’ve experienced side effects on Mounjaro, consider starting on a lower Wegovy dose to help reduce the chance of new side effects when switching.

Wegovy dose options:

Equivalent Icon Equivalent dose: 1.7mg Step down Icon Step-down dose: 1mg
If you’ve experienced side effects on Mounjaro, consider starting on a lower Wegovy dose to help reduce the chance of new side effects when switching.

Wegovy dose options:

Equivalent Icon Equivalent dose: 2.4mg Step down Icon Step-down dose: 1.7mg
If you’ve experienced side effects on Mounjaro, consider starting on a lower Wegovy dose to help reduce the chance of new side effects when switching.

Wegovy dose options:

Equivalent Icon Equivalent dose: 2.4mg Step down Icon Step-down dose: 1.7mg
If you’ve experienced side effects on Mounjaro, consider starting on a lower Wegovy dose to help reduce the chance of new side effects when switching.

Benefits of Wegovy

Wegovy supports effective weight loss and long-term maintenance, while also offering health and lifestyle benefits. Below are some of the key benefits compared to Mounjaro:

  • Effective weight loss: 15–17% average at 2.4 mg; upcoming 7.2 mg dose results in up to 21% average weight loss, with a third of patients losing more than 25%.
  • Fewer injection reactions: Only 1.4% experience mild site reactions vs 3.2% with Mounjaro.
  • More cost-effective: Considerably lower price than Mounjaro.
  • No impact on oral contraceptives.
  • Heart health support: Reduces risk of heart attack or stroke in those with heart disease.
  • Kidney protection: Helps lower risk of serious kidney problems in type 2 diabetes with kidney disease.

Will Wegovy's price increase?

Novo Nordisk has issued a public statement confirming that there are no plans to change Wegovy’s price in the UK:

“We currently have no plans of changing our offering in the UK. Our focus is on supporting patients, and we are committed to ensuring that our medicines are not only innovative but also accessible and affordable for those who need them most. Our mission is to help create a healthier world by addressing some of the most pressing threats to public health – including obesity, diabetes, and cardiovascular disease.”

This means that Wegovy remains a stable, cost-effective option for weight management in the UK.

Weight maintenance

After reaching your weight loss goals, maintenance doses of Mounjaro or Wegovy can help you keep the weight off.

We can continue prescribing treatment as long as your weight and BMI remain within a healthy range. Choosing the right dose and schedule is a personal decision, and our clinicians will tailor your plan to support safe, sustainable long-term results.

Tip: When thinking about long-term treatment, consider both how the dose fits with your lifestyle and your budget.

Contraception and Wegovy

Wegovy is not known to affect oral contraceptives, unlike Mounjaro, which may reduce their effectiveness, especially in the first few weeks after starting or increasing your dose.

If you’re taking Mounjaro, consider a non-oral method (coil, injection, patch) or use a barrier method such as condoms for extra protection. Include details about your current contraception in your consultation, and our clinicians will advise on the safest option for you.

Heart protection with Wegovy

Wegovy is licensed to reduce the risk of serious heart problems, such as heart attack or stroke, in adults who are overweight or obese and have existing heart disease.

If you have heart disease or risk factors like high blood pressure or high cholesterol, you may be eligible for Wegovy. Our clinicians will consider your medical history during your consultation to ensure it is a safe and suitable option for you.

Frequently Asked Questions

Why has the price of Mounjaro increased?

Eli Lilly, the manufacturer of Mounjaro, has increased the price of all dose strengths in the UK to bring them in line with prices across mainland Europe.

This means that in the UK, Wegovy is now generally the more cost-effective GLP-1 option for weight management.

We know price changes can feel frustrating and unexpected. Our priority is to help you continue your weight loss journey with as little disruption as possible, and to find the treatment that best supports your health goals and lifestyle.

I can’t afford Mounjaro going forward. Can I switch to another medication?

Yes. With the new Mounjaro prices, Wegovy is now the more cost-effective option for weight loss and weight maintenance.

Switching between medicines is a normal part of managing long-term health, and our clinicians do this regularly to help patients reduce side effects, manage costs, or adapt to treatment availability. We’ll work with you to find the option that fits your health needs, lifestyle, and budget.

Do you recommend switching from Mounjaro to Wegovy?

Our priority is to keep you moving forward in your weight loss journey with as little disruption as possible.

If you’re tolerating Mounjaro well and the new price is manageable for you, there’s no need to switch. But if the cost is a barrier, Wegovy offers a highly effective alternative with some added benefits, including reduced cardiovascular risk.

If you choose to switch, our clinical team will make sure the change is safe and smooth, so you can continue working towards your goals with confidence.

Is Wegovy as effective as Mounjaro in the long term?

Clinical trials show that Mounjaro leads to greater average weight loss compared to Wegovy, and as of August 2025, it remains the most effective treatment available.

That said, Wegovy is still very effective. At the current maximum licensed dose (2.4 mg), people lose around 15–17% of their body weight on average over 68 weeks. Later this year, a higher-strength Wegovy (7.2 mg) is expected to launch (around November–December 2025).

Early trial data suggests this dose may deliver an average weight loss of 21%, with around one in three patients losing 25% or more. This is higher than the results seen with Mounjaro.

Wegovy also offers additional benefits, including:

  • Support for heart health, with reduced cardiovascular risk
  • Does not reduce the effectiveness of oral contraceptives
  • Lower cost compared to Mounjaro
  • Less likely to cause injection site reactions

Will I experience side effects on Wegovy if I switch from Mounjaro?

Wegovy and Mounjaro work in similar ways, so they can cause similar side effects. If you tolerate Mounjaro well, you’re less likely to notice new or worse side effects when switching to an equivalent Wegovy dose.

The most common side effects include nausea, diarrhoea, constipation, stomach pain, vomiting, headaches, or tiredness. These are usually mild and temporary, especially as your body adjusts.

If you experience side effects on your current Mounjaro dose, or are concerned about them, your clinician may suggest stepping down one dose when switching to reduce the risk.

We provide guidance and resources on managing side effects, including videos and practical tips, and you can always contact our team if you need support.

Could my weight plateau or increase when I switch?

Most people don’t gain weight when switching, but some notice a short pause in progress before weight loss continues. Others keep losing steadily, and some even see things speed up again after a few weeks.

The best way to stay on track is to follow your injection schedule closely and keep up with your healthy lifestyle changes.

Will I receive support when I switch to Wegovy?

Yes. We’ll guide you through the switch and provide helpful resources, including instructions on how to use Wegovy, how to store it safely, and tips for managing side effects.

We usually follow up every 1–2 months to see how you’re getting on and whether any adjustments could help. You can also contact us at any time if you have questions.

Will I have to start over at the lowest dose of Wegovy?

Usually not. Your starting dose will depend on your current Mounjaro dose and how long you’ve been taking it. You can use our dosage guide earlier on this page to see which dose might be suitable for you.

In some cases, we may recommend starting on a lower Wegovy dose to make the transition easier and reduce the risk of side effects. This doesn’t mean you’re starting over, it’s a safe way to help your body adjust while keeping your progress on track.

Our goal is always steady, sustainable weight loss that works for you in the long term.

Can Wegovy help with kidney health?

In people with type 2 diabetes and chronic kidney disease, Wegovy has been shown to significantly reduce the risk of serious kidney problems and related complications.

If you have kidney concerns or a diagnosis, you can share this in your consultation. Our team will assess your medical history and advise on whether Wegovy could be suitable for you.

Medically reviewed by Dr. Plauto Filho Written by our editorial team Last reviewed 21-08-2025
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