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- Menopause
- Sandrena
Sandrena Gel
Buy Sandrena Gel after completing our online consultation for menopause symptoms
Prices include next-day delivery and prescription
| 3 months £44.99 | 3 packs x 28 sachets |
| 6 months £74.99 | 6 packs x 28 sachets |
Select your treatment after the consultation:
Benefits of product
Smooth, daily relief in a quick-drying gel
- Daily fast-absorbing oestrogen gel
- Suitable for women with or without a womb.
- Relieves common symptoms such as hot flushes.
- Single-use sachets for simple, hygienic application.
- Ideal for women who prefer non-patch or non-tablet options.
Sandrena vs Oestrogel
Sandrena gel and Oestrogel are both highly effective forms of topical HRT. But they each offer unique benefits. See how they compare below.
 Sandrena Gel |
 Oestrogel |
|
|---|---|---|
| Format | Single-use sachets | Pump-action bottle |
| Application | Apply once daily to lower body or thighs | Apply once daily to arms or legs |
| Texture & absorption | Light gel, fast-absorption | Slightly thicker gel, takes a bit longer to dry |
| Dose measurement | Pre-measured sachets for simple daily use | Adjustable pump doses |
| Packaging | Individual sachets - easy for travel | Single bottle with measured pumps |
| Who it may suit | Those who prefer set doses and tidy sachets | Those who prefer pump-controlled flexible dosing |
How to use Sandrena
Applying the gel
Spread the gel onto your lower body or thighs, switching sides each day.
Let it absorb
Allow the gel to absorb for 1-2 minutes before putting on any clothing.
Wash your hands
You should wash your hands after applying the gel. Avoid others touching the area until it dries.
Key facts
| Type of medicine | HRT (hormone replacement therapy) |
| Used for | Menopausal symptoms |
| Active ingredient | Estradiol |
| Works by | Supplementing oestrogen to help relieve menopause symptoms. |
| Effective within | 3 months |
| Available as | Transdermal gel |
| Available dosage(s) | 1 mg |
| Usage instructions | Apply 1 sachet (1 mg) of gel to your lower body or thighs, spreading it evenly over an area roughly 1-2 times the size of your hand |
| Packaging | Smooth, pale gel in single-use sachets; each pack contains 28 sachets |
| Manufacturer | Orion pharma |
| Generic available? | No |
| Storage | Do not store above 25°C |
Excellent
4.7
26,973 patients have reviewed our service on Trustpilot
Stuart D , 22 Apr
product as described, good price and promptly dispatched.
Mr Parker , 22 Apr
My original card was compromised. My new card number was accepted without problems. I then received my medication promptly.
David K , 21 Apr
next day delivery always arrives on time
Jennifer A , 21 Apr
Always fast and reliable service
Richard F , 20 Apr
Good selection of products to choose from after the consultation period, the questions do seem thorough to reach a conclusion. Th product I chose was delivered fast and with fantastic communication, I wouldn’t hesitate to recommend these people. Thank you to all .
Febiola L , 20 Apr
Easy to order and smooth delivery throughout.
Sally C , 20 Apr
Easy to order Quick delivery
Mrs fredericks , 20 Apr
Order arrived late. Ice pack had completely melted.
Mark , 20 Apr
I had a lot of trouble with reordering from the website. At the final stage the site was endlessly buffering. I accessed my account again from a different web browser and the same thing happened. The online chat wasn’t much help, advising me to delete my history and try again - no joy. Then I was asked to call the helpline. When I did this I was informed there was no one available and asked to leave a message, which I did. No one called back. It was only on the second occasion that I got through to a person who confirmed my order. In the days following I was bombarded by electronic emails telling me I had an incomplete order (which I didn’t) and asking if a needed help (!)
More information about Sandrena
About Sandrena
What is Sandrena gel?
Sandrena is a type of HRT manufactured by Orion. It is available in the form of a gel that comes in single-use sachets. It helps to improve menopausal symptoms such as hot flushes, night sweats and vaginal dryness by helping to balance your hormone levels.
Does Sandrena contain progesterone?
No, Sandrena only contains oestrogen. You will need to take a progesterone if you have a womb to stop the lining of the womb from thickening too much. This helps to reduce the risk of cancer of the womb (endometrial cancer).
How does Sandrena work?
Sandrena contains estradiol, which is a synthetic form of the reproductive hormone oestrogen. During menopause, oestrogen levels fall, which is what causes symptoms. Sandrena therefore works by restoring your oestrogen levels, reducing these symptoms.
What are the benefits of Sandrena gel?
There are several benefits of using Sandrena. As well as reducing the severity of menopause symptoms, it has a lower risk of side effects compared to oral HRT. This is because it is absorbed into the skin, bypassing the digestive system and the liver.
Using Sandrena
When do I start Sandrena?
You can start Sandrena straight away if you have never used HRT or you are changing from a period-free HRT. If you are changing from a HRT that causes a period, you should wait for your period to end before starting Sandrena. .
How much Sandrena gel should I use?
Each Sandrena sachet contains 1 mg of the gel. The typical dose is one sachet per day (1 mg). But you can use 0.5 - 1.5 mg daily. .
Always follow the instructions from your doctor or specialist..
How do I apply Sandrena gel?
You apply Sandrena gel directly to the skin.
- Apply the gel to your lower body or thighs. Try to switch sides each day.
- Spread the gel over an area of skin that is 1-2 times the size of your hand.
- Allow the gel to dry for a few minutes.
- Wash your hands after applying the gel. Avoid getting the gel in your eyes as it can cause irritation.
- Do not let anyone touch the area of the skin where the gel was applied until it has dried.
Allow the gel to absorb before showering, swimming or doing heavy exercise.
What happens if I miss a dose?
If you are less than 12 hours late, apply the gel as soon as you remember. If you are more than 12 hours late, skip the missed dose and take the next dose at the usual time. Missing doses may cause bleeding between periods (breakthrough bleeding).
Safety and precautions
Who cannot use Sandrena?
Sandrena gel is safe for most women to use to relieve menopause symptoms.
Do not use Sandrena gel if you have:
- ever had breast cancer
- a cancer which is sensitive to oestrogen, such as endometrial cancer (cancer of the womb)
- any unexplained vaginal bleeding
- a blood-clotting disorder
- had a heart attack, stroke or angina (conditions caused by blood clotting)
- a liver disease or irregular liver function test results
- an inherited blood condition called porphyria
- bleeding on the brain
What are the most common side effects of Sandrena?
Common side effects of Sandrena gel include:
- itchy skin or rashes
- increased sweating
- swollen feet and lower legs
- tender or painful breasts
- weight changes
- headache
- dizziness
- stomach pain
- feeling sick
- depression or nervousness
- hot flushes
- bleeding or spotting
This is not a complete list. For a full list of side effects, please refer to the patient information leaflet.
How safe is Sandrena?
Sandrena gel is safe, provided you get a prescription from a licensed healthcare professional. It was approved for use in the UK in November 1996, and since then has been a trusted product for thousands who rely on it for effective HRT treatment.
However, as with all HRT medicines, it can pose some risk. You should take special care if you have a condition that makes you more likely to get a blood clot. Speak with your doctor if you’re unsure about the safety of treatment with Sandrena gel.
