• Absorbs 30% of fat intake
  • UK's only prescription weight loss pills
  • Promotes a healthy lifestyle

Xenical (orlistat) is proven to be twice as effective as dieting and exercise alone. These weight loss pills work to absorbs fat rather than influence the brain making it far safer. To order Xenical today, complete our free online consultation to be reviewed by one of our partner doctors. On all orders before 4.30pm, Xenical will be sent for next working day delivery. Our whole process is discreet and fast.

Xenical is under review by our partner doctors and orders have been currently stopped. For more information on alternative treatments to weight loss, please visit our weight loss information page.
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What is Xenical?

Xenical (orlistat), unlike other unregulated diet pills and remedies, is currently the only clinically proven weight loss drug available to help people with a body mass index (BMI) over 30 in the UK. Unlike most past weight loss medications, these weight loss tablets work directly in the stomach and doesn't influence the hormonal balances in the brain. Xenical works by preventing up to 30% of the fat you consume per meal from being absorbed and taken to your body's fat stores. In clinical trials, it has been proved to be effective, and helped participants lose between 5% and 10% of their body weight during each cycle of use.

How Orlistat works

There is no doubt that following a healthy, balanced diet and doing a reasonable amount of exercise is the only way to lose weight and keep it off over the long term. However, if your health is at risk and you are struggling to lose weight, using a weight loss treatment such as Xenical can help make your efforts more successful.

How does Xenical work?

Xenical (orlistat) tablets contain the active ingredient orlistat (i.e. generic orlistat), which doesn't work in the brain. This means it won't influence your mood and makes the effects of this medication more predictable. Once in your body, Xenical works to prevent enzymes from breaking down fat so that it can be absorbed by your digestive system and stored. This means that a third of the fat per meal you consume gets blocked and just passes through your system, working essentially as a fat blocker. We also recommend that you use a vitamin supplement when you take this medication, as some vitamins are absorbed with the fat you consume.[1]

Fat digestion Duodenum Orlistat From the pancreas Lipase Duodenal mucosa Fat
Duodenal mucosa Orlistat - Mechanism of action Duodenum Orlistat From the pancreas Lipase Duodenal mucosa Fat
Duodenal mucosa
Structural formula of orlistat

What are the benefits of Xenical?

Xenical (orlistat) is currently the only available prescription weight loss medication to help people to lose weight. If combined with a healthy diet (preferably with a fat content of around 30% or less) and exercise, it can provide noticeable results within 2 to 3 months of starting treatment.

The benefits of taking Xenical obviously transfer into your health, and you'll notice this sooner than you think too. Not only will be feel healthy, have far more energy and loads more self-confidence, losing weight can reduce your chances of developing problems such as; high blood pressure, high cholesterol, heart disease and diabetes.

The difference between fat blockers and appetite suppressants

This can be confusing, so let us explain; fat blockers work directly in your stomach by allowing fat to pass through your body instead of being stored (as mentioned above) whilst appetite suppressants triggers the brain into thinking you're full.

There are two main pluses of choosing a fat blocker rather than an appetite suppressant:

  • You don't have to revise and overhaul your current diet – yes, positive changes should be made to your diet when losing weight, regardless of whether you decide to take prescription medication or not, however this is not as radical, which means you have more of a chance at making realistic decisions and continuing to improve. No crash diets, and fewer restrictions.
  • There is no connection with the brain – the danger with appetite suppressants is their connection to the brain that can in rare cases lead to mental health issues. Whilst fat blockers directly target the stomach, and therefore the source of the problem.

How do I take Xenical?

You can purchase Xenical pills online if you are over 18 and your BMI is over 30, or if you have a BMI of 27 combined with underlying weight-related health conditions that may be putting your life at risk.

Xenical (orlistat) is currently only available on prescription at a 120mg. Using the medication is simple and guidelines are as follows:

  • One 120mg Orlistat capsule is the recommended dose
  • It should be taken with a full glass of water during or at the latest one hour after each meal, three times a day.
  • Still take a pill even if you feel you have had a meal with low fat content

How does Xenical differ from Reductil?

Like Xenical (orlistat), Reductil was a prescription weight loss treatment that was used as an aid for effective weight loss when combined with a balanced diet. However unlike Xenical, which does not affect the brain, Reductil was a psychological treatment that worked in the central nervous system. It worked by making the user feel fuller quicker, while repressing the person's appetite. The European Medicines Agency (EMA) deemed Reductil a dangerous medication, increasing the risk of heart attack or stroke, hence why it has been discontinued and is not available to buy anywhere. Alternatively, Xenical works directly in the stomach preventing up to 30% of the fat you consume in each meal from being absorbed.

Clinical trials showed that Xenical proved to be a safe and effective weight loss treatment when used alongside a well balanced diet and physical exercise.

What are the side effects of Xenical?

Similar to other prescription medications, side effects may occur when using the treatment. The severity of the potential side effects varies from person to person. This means that while some may have to deal with more severe side effects, others won't experience any at all. Xenical (orlistat) tablets can cause changes in your bowel, which can include an increase in bowel movements, flatulence (with an oily discharge) and abdominal pain.[2]Other common side effects can include:

  • Diarrhoea
  • Low blood sugar
  • Tiredness
  • Incontinence

These are not usually common and should lessen as the body becomes accustomed to the medication. Very rare side effects that have been recorded are rectal bleeding, hepatitis, blistering and allergic reactions but these are highly unlikely. If you do however experience any of these side effects, you should contact a doctor, or your GP, to discuss your situation further.

What are the precautions/interactions of Xenical?

Before committing to purchasing Xenical (orlistat) online, you should check over the precautions when taking the treatment. It is vital that you are aware of the side effects of this drug and how you can go about avoiding them. People that may be unsuitable to use this treatment includes:

  • Pregnant women (or women who are breastfeeding)
  • Those with allergic reactions to the active ingredient orlistat
  • Those with gallbladder problems (cholestasis)
  • Those with thyroid disorders
  • Those with kidney stones or kidney problems
  • Those with eating disorders

Overall however, the majority of people who wish to use Xenical can, with little to no side effects. For any additional information, please refer to our patient leaflet.

How can I buy Xenical online safely?

Buying prescription medicines online is becoming increasingly popular, especially when obtaining recurrent medication. You can buy Xenical 120mg safely online here from HealthExpress by taking our online consultation and ordering the treatment after an approval has been provided by one of our partner doctors. If you do, you can then expect to receive the treatment the very next day (if ordered before 4pm) or the same day (if within London).

Dr Hilary Jones Independent Medical Adviser

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