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Excellent 4.8 | 98 customers reviewed us
Dr. Sarah Donald
Dr. Sarah Donald Clinical Lead

"Our medical team is always on hand to ensure that you get the safest and most effective treatment. Your medication will be dispatched the same day from our pharmacy."

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Xenical FAQs

What is Xenical?

Xenical (orlistat) is a clinically proven weight loss drug available to help people with a body mass index (BMI) over 30. Xenical works by preventing up to 30% of the fat you consume per meal from being absorbed and taken to your body's fat stores. It has been proved to be effective in clinical trials, where it showed that it was possible for participants to lose between 5% and 10% of their body weight during each cycle of use.

How Orlistat works Xenical Weight Loss Obesity

There is no doubt that following a healthy, balanced diet and doing a reasonable amount of exercise is the only way to lose weight and keep it off over the long term. However, if your health is at risk and you are struggling to lose weight, using a weight loss treatment such as Xenical can help make your efforts more successful. However, it is important to follow a healthy diet during the treatment with Xenical to avoid unpleasant side effects.

How does Xenical work?

Xenical tablets contain the active ingredient orlistat. Once in your body, Xenical works to prevent enzymes from breaking down fat so that it can be absorbed by your digestive system and stored. This means that a third of the fat per meal you consume gets blocked and just passes through your system, working essentially as a fat blocker. We also recommend that you use a vitamin supplement when you take this medication, as some vitamins are absorbed with the fat you consume.

Fat digestion Duodenum Orlistat From the pancreas Lipase Duodenal mucosa Fat
Duodenal mucosa Orlistat - Mechanism of action Duodenum Orlistat From the pancreas Lipase Duodenal mucosa Fat
Duodenal mucosa
Structural formula of orlistat

What are the benefits of Xenical?

If combined with a healthy diet (preferably with a fat content of around 30% or less) and exercise, Xenical (orlistat) can provide noticeable results within 2 to 3 months of starting treatment. Achieving a healthier weight can reduce your chances of developing problems such as; high blood pressure, high cholesterol, heart disease and diabetes.

It is important to note that Xenical should never be the only measure taken to tackle weight loss. The prescription treatment can be used in conjunction with an adjusted diet and increased exercise to support weight loss, but should not be used on its own as this can lead to unpleasant side effects.

How do I take Xenical?

You can purchase Xenical pills online if you are over 18 and your BMI is over 30, or if you have a BMI of 28 combined with underlying weight-related medical conditions that may be putting your health at risk.

Xenical (orlistat) is currently only available on prescription at a dose of 120mg. Using the medication is simple and guidelines are as follows:

  • One 120mg Orlistat capsule is the recommended dose
  • It should be taken with a full glass of water during or at the latest one hour after each meal, three times a day.
  • Still take a pill even if you feel you have had a meal with low fat content

It is important to monitor the weight loss you achieve whilst taking this treatment. If you have lost less than 5% of your starting weight after 12 weeks of treatment, you should consult your doctor about continuing your treatment.

If you fail to achieve this goal, the standard procedure is to cease the treatment with Xenical. If you suffer from diabetes, a goal of a 3% weight reduction after 12 weeks may be sufficient to continue the treatment. Equally, special circumstances may allow you to keep taking Xenical despite not achieving your weight goal, your doctor will be able to advise in these cases.

How does Xenical differ from other treatments such as Reductil?

Before a doctor prescribed a prescription drug to aid weight loss, the patient is normally expected to have previously gone through different treatment options based on diet and exercise plans. If the results of these measures were not satisfactory in reducing the health risks associated with obesity, a prescription treatment may be considered.

Like Xenical (orlistat), Reductil was a prescription weight loss treatment that was used as an aid for effective weight loss when combined with a balanced diet. Reductil worked in the central nervous system by making the user feel full more quickly and repressing the person's appetite.

The European Medicines Agency (EMA) deemed Reductil a dangerous medication, due to an increased risk of heart attack or stroke. This treatment has therefore been discontinued and is no longer available.

Clinical trials have shown that Xenical is considered a safe and effective weight loss treatment when used according to your doctor's recommendations alongside a well-balanced diet and physical exercise.

In extreme cases, surgical procedures such as the insertion of a gastric band may be recommended to significantly reduce weight long term. Before you consider any medication or surgical procedure, you should discuss all options with your doctor and/or nutritionist.

What are the side effects of Xenical?

Similar to other prescription medications, side effects may occur when using the treatment. The severity of the potential side effects varies from person to person. This means that while some may have to deal with more severe side effects, others won't experience any at all. Xenical (orlistat) tablets can cause issues in your gastrointestinal tract, which can include an increase in bowel movements, flatulence (with an oily discharge) and abdominal pain. Other common side effects can include:

  • Diarrhoea, fatty or oily stools
  • Low blood sugar
  • Tiredness
  • Incontinence

These are not usually common and should lessen as the body becomes accustomed to the medication. Very rare side effects that have been recorded are rectal bleeding, hepatitis, blistering and allergic reactions but these are highly unlikely. If you do however experience any of these side effects, you should contact a doctor, or your GP, to discuss your situation further.

Please note: a diet high in fat may increase the occurrence of side effects and should be avoided during the full course of treatment.

What are the precautions/interactions of Xenical?

Before committing to purchasing Xenical (orlistat) online, you should check the precautions known for this treatment. It is vital that you are aware of the side effects of this drug and how you can go about avoiding them. Certain circumstances increase the risk of dangerous side effects and the following risk groups are excluded from the treatment with Xenical:

  • Pregnant women (or women who are breastfeeding)
  • Those with allergic reactions to the active ingredient orlistat
  • Those with gallbladder problems (cholestasis)
  • Those with thyroid disorders
  • Those with kidney stones or kidney problems
  • Those with eating disorders

Overall however, the majority of people who wish to use Xenical can, with little to no side effects. For any additional information, please refer to our patient leaflet or consult your doctor.

How can I buy Xenical online?

Buying prescription medicines online is becoming increasingly popular, especially when obtaining recurrent medication. You can buy Xenical 120mg online from HealthExpress by taking our online consultation. If you do, you can then expect to receive the treatment the very next day.

Can I buy Xenical without a prescription?

Xenical is a prescription only medication. This means you must gain approval from a doctor before using it, whether this is online or in-person. Xenical can cause side effects and interact with other medication which is why it is important for a doctor to assess your medical history and rule out any potential health risks.

Is it safe to buy Xenical online?

Our doctor reviews every questionnaire to ensure the medication is completely safe for you to use. Xenical is prepared by our UK pharmacy. If our doctor doesn't offer you a prescription for Xenical, our customer service will contact you. It could be that Xenical isn't suited to you or we require further information.

Our service has all the relevant and mandatory safety certificates including the Medicines & Healthcare Products Regulatory Agency (MHRA), General Medical Council (GMC) and the General Pharmaceutical Council (GPC).

If you have any questions about our service or this medication, please contact our customer service team and one of our friendly advisors will assist you with any queries.

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