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- Menopause
- Elleste Duet
Elleste Duet
Buy Elleste Duet after completing our online consultation for menopause symptoms
Prices include next-day delivery and prescription
| 3 months £21.99 | 84 tablets |
| 6 months £39.99 | 168 tablets |
Select your treatment after the consultation:
Benefits of product
Combined hormonal support for symptoms of menopause
- Effective relief from hot flushes, night sweats, and insomnia
- Combination HRT for women with a womb
- Bioidentical hormones for natural menopause support
- Simple once-daily tablet
- 1 mg + 1 mg/1 mg & 2 mg + 2 mg/2 mg film-coated tablets
Elleste products compared
There are 3 different versions of Elleste: Elleste Solo, Elleste Duet, and Elleste Duet Conti. The one that’s right for you depends on your individual circumstances. Here is a helpful table explaining the main differences:
 Elleste Solo |
 Elleste Duet |
 Elleste Duet Conti |
|
|---|---|---|---|
| Type of HRT | Oestrogen-only | Combined oestrogen + progestogen (sequential/cyclical) | Combined oestrogen + progestogen (continuous) |
| Active ingredient(s) | Estradiol hemihydrate | Estradiol hemihydrate & norethisterone acetate | Estradiol hemihydrate & norethisterone acetate |
| Suitable for | Postmenopausal or perimenopausal women without a womb (hysterectomy). | Postmenopausal or perimenopausal women with a womb, including recent bleeding. | Postmenopausal women with a womb who need continuous HRT. |
| Monthly bleed? | No | Yes | No |
How to use Elleste Duet
Start right
If you’re still having regular periods, start on the first day of bleeding, if not, you can start right away.
Take the right tablet
Each pack will have two coloured tablets. Take one per day, starting with the first one and following the arrows.
Follow your doctor’s advice
Elleste Duet should be taken only as long as necessary. Your doctor will tell you how long to take it for.
Key facts
| Type of medicine | Hormone replacement therapy (HRT) |
| Used for | Menopausal symptoms |
| Active ingredient | Estradiol hemihydrate & norethisterone acetate |
| Works by | Replacing depleted oestrogen levels while protecting the uterine lining |
| Effective within | A few weeks, with peak effects felt after approximately 3 months |
| Available as | Tablets |
| Available dosage(s) | 1 mg & 2 mg |
| Usage instructions | Take 1 tablet at the same time every day, following the order of the strip |
| Packaging | Blister packs containing 28 tablets each (84 total) |
| Manufacturer | Exeltis |
| Generic available? | No |
| Storage | 1 mg: store below 30°C 2 mg: store below 25°C Store tablets in the original packaging |
Excellent
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27,066 patients have reviewed our service on Trustpilot
Evelyn J , 12 May
An excellent service and prompt.
Maggie W , 12 May
Delivered on time and instructions for storing and using emailed
Paul , 11 May
Excellent consultation service. Prompt delivery service and affordable pricing. Well done Health Express. I will definitely use your service for my future prescriptions.
Tracey O , 11 May
Good service but need discounts more often as I keep missing them. Staff are always polite on the phone. Not had any delivery problems.
Kate , 11 May
Straightforward application and fast delivery
Mr C , 11 May
Great price, swift delivery!
Matt W , 11 May
Fast delivery
Steve W , 11 May
Great service
Guest , 10 May
The people on phone are polite and helpful also the delivery is always on time
More information about Elleste Duet
About Elleste Duet
What is Elleste Duet?
Elleste Duet is an HRT medication that combines oestrogen and progestogen to help ease menopause symptoms while protecting your uterine lining. It is suitable for women who still have their womb, including those who are perimenopausal or still having periods, as progestogen makes you less likely to experience excessive thickening of the endometrium than oestrogen-only HRTs.
Elleste Duet follows a sequential regimen, meaning oestrogen is taken every day and progestogen is added for part of the month. Taken in the order set in the pack, this helps manage menopause symptoms like hot flushes, sleep problems, mood swings, and more, while mimicking a natural menstrual cycle.
It is available from HealthExpress in the form of 1 mg and 2 mg tablets.
How does Elleste Duet work?
Elleste Duet is an HRT that supplements oestrogen lost during menopause and includes progestogen to protect the lining of your uterus. Its effects come from these two active ingredients:
- Estradiol: binds to oestrogen receptors to increase hormone levels in the body, alleviating menopausal symptoms like night sweats, hot flushes, and sleep problems.
- Norethisterone: a progestogen that protects the womb lining (endometrium) from excessive thickening. This protects you from discomfort and reduces your risk of endometrial cancer.
This dual-action support helps you take back control of your hormones during menopause, helping you regain balance and confidence.
Is Elleste Duet a good HRT?
Elleste Duet is generally well-tolerated and highly effective, helping women ease symptoms and regain balance. It’s generally considered a reliable, effective option for managing hot flushes, night sweats, mood changes, and other menopause symptoms, especially for women who still have a womb and need a treatment containing both oestrogen and progesterone.
Using Elleste Duet
How do I take Elleste Duet?
Take 1 tablet every day with a glass of water. You can take Elleste Duet at any time of day, just make sure you take every tablet at around the same time to ensure a steady supply of hormones.
Each strip of tablets will have two different colour tablets. Start with the first one in the pack, and follow the arrows to ensure you take your next ones in the correct order. Continue taking tablets every day until the strip is finished, and then start your next one without a break.
Your doctor will let you know how long you should take this treatment for. You should be prescribed the lowest effective dose to minimise the risk of side effects.
When should I start taking Elleste Duet?
When you start taking Elleste Duet depends on whether or not you still have menstrual periods:
- If you still have regular periods, take your first tablet on the first day of bleeding.
- If you are not having regular periods, you can start straight away.
If you are switching from another oral HRT, start taking Elleste Duet once you finish the one you are currently taking. If you are switching from another type of HRT (e.g. patches), speak to your doctor about how to switch safely and effectively, as advice depends on what you’re switching from.
How long does Elleste Duet take to work?
Elleste Duet works instantly to supply your body with hormones, but it can take a few weeks for you to notice an improvement in your symptoms. Peak effects are usually felt about 3 months after you take your first tablet, and continuously support you until you stop taking it.
Does Elleste Duet cause weight gain?
Some women notice changes in weight while taking Elleste Duet, but it isn’t clear whether this is a result of Elleste Duet directly, or of menopause itself.
Lower oestrogen levels as a result of menopause have been linked to weight gain due to factors like reduced activity levels, overeating, and changes to metabolism. If weight gain has been experienced as a result of hormone changes, then Elleste Duet may indirectly support you in this way. Weight gained may also be water weight as a result of fluid retention, and should only be temporary.
Safety and precautions
Who can take Elleste Duet?
Elleste Duet can be safely taken by postmenopausal women who still have a womb, provided treatment is deemed safe in our short online consultation.
Do not take Elleste Duet if you have:
- an allergy to estradiol, norethisterone, or any other ingredient found in this medicine
- ever had breast cancer
- cancer that is sensitive to oestrogens, such as endometrial cancer
- unexplained vaginal bleeding
- excessive thickening of the womb lining (endometrial hyperplasia) that is not being treated
- ever had a blood clot, or a condition that affects clotting
- or recently had a disease caused by blood clots in the arteries
- ever had liver disease and your liver function tests have not returned to normal
- porphyria, a rare inherited blood disease
During your consultation, tell your doctor about any health conditions and medications you use to make sure your treatment is safe for you.
What are the most common side effects of Elleste Duet?
Elleste Duet can cause side effects, but not everyone will get them. Tell your doctor if you experience any side effects as a result of taking this medicine.
The most common Elleste Duet side effects include:
- headache
- breast pain
- breast tenderness
- painful periods
- changes to your menstrual cycle
- mood changes
This is not an exhaustive list. For a full list of Elleste Duet’s side effects, consult the patient information leaflet .
How safe is Elleste Duet?
Elleste Duet is safe provided you are prescribed treatment from a licensed healthcare provider like HealthExpress. Elleste Duet was approved for use in the UK in 1997, meaning it has a long track record of clinical use and monitoring.
If you no longer have a womb, you may be prescribed an oestrogen-only HRT like Elleste Solo since you are not at risk of endometrial problems.
